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Revision as of 19:41, 23 June 2016

Asplenia Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Asplenia from other Diseases

Epidemiology and Demographics

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Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Natural History

Complications

Asplenia increases the risk of septicaemia from encapsulated bacteria, and can result in a syndrome known as overwhelming post splenectomy infection (OPSI) which can kill within a few hours. In particular patients are at risk from Pneumococcus, but also Haemophilus influenzae & Meningococcus.

The risk to asplenic patients has been expressed as equivalent for a child to die in home accident, and for adults dying in a road traffic accident (reference UK Splenectomy Trust Advice) - so sensible precautions are needed, but no panic.[1]

Prognosis

References

  1. "Splenectomy and Infection" (PDF). Splenectomy Trust. March 2002. Retrieved 2006-12-12. - reprint from Kent and Medway NHS and Social Care Partnership Trust


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