Angiomyolipoma epidemiology and demographics: Difference between revisions

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{{Angiomyolipoma}}
{{Angiomyolipoma}}
{{CMG}}''' Associate Editor-In-Chief:''' {{CZ}}, {{Faizan}}
{{CMG}}''' Associate Editor-In-Chief:''' {{CZ}}, {{Faizan}}, {{Rekha}}
==Overview==
The [[incidence]] of [[angiomyolipoma]] is approximately 30 per 100,000 individuals worldwide. Females are more commonly affected with [[angiomyolipoma]] than males. [[Angiomyolipoma]] commonly affects individuals older than 40 years of age.
==Epidemiology and Demographics==
===Prevalence===
 
* [[Angiomyolipoma]] occurs in more than 70% of cases with renal manifestations of [[tuberous sclerosis]].<ref name="pmid17003820">{{cite journal| author=Rakowski SK, Winterkorn EB, Paul E, Steele DJ, Halpern EF, Thiele EA| title=Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors. | journal=Kidney Int | year= 2006 | volume= 70 | issue= 10 | pages= 1777-82 | pmid=17003820 | doi=10.1038/sj.ki.5001853 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17003820  }}</ref><ref name="pmid170038202">{{cite journal| author=Rakowski SK, Winterkorn EB, Paul E, Steele DJ, Halpern EF, Thiele EA| title=Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors. | journal=Kidney Int | year= 2006 | volume= 70 | issue= 10 | pages= 1777-82 | pmid=17003820 | doi=10.1038/sj.ki.5001853 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17003820  }}</ref><ref name="pmid15327383">{{cite journal| author=Bissler JJ, Kingswood JC| title=Renal angiomyolipomata. | journal=Kidney Int | year= 2004 | volume= 66 | issue= 3 | pages= 924-34 | pmid=15327383 | doi=10.1111/j.1523-1755.2004.00838.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15327383  }}</ref>
 
===Incidence===


==Overview==
* The [[incidence]] of [[angiomyolipoma]] is approximately 30 per 100,000 individuals worldwide.
 
===Gender===
 
* Females are more commonly affected with [[angiomyolipoma]] than males. The female to male ratio is approximately 4 to 1.
 
===Age===


Angiomyolipomas are the most common benign solid renal lesion and also the most fat containing lesion of the kidneys. The majority of angiomyolipomas are sporadic (80%) and are typically identified in adults (mean age of presentation 43 years), with a strong female predilection (F:M of 4:1) 7,9. The remaining 20% are seen in association with phakomatoses, the vast majority in the setting of tuberous sclerosis, although they have also been described in setting of Von Hippel-Lindau syndrome (VHL) and neurofibromatosis type 1 (NF1) 5,7. In these cases they present earlier (usually identified by the age of 10 years), are larger, and are far more numerous. They are more likely to be fat-poor which accounts for their earlier presentation 2,6-7.
* [[Angiomyolipoma]] commonly affects individuals older than 40 years of age.<ref name="pmid20635448">{{cite journal| author=Koo KC, Kim WT, Ham WS, Lee JS, Ju HJ, Choi YD| title=Trends of presentation and clinical outcome of treated renal angiomyolipoma. | journal=Yonsei Med J | year= 2010 | volume= 51 | issue= 5 | pages= 728-34 | pmid=20635448 | doi=10.3349/ymj.2010.51.5.728 | pmc=2908871 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20635448  }}</ref>


==Incidence==
The incidence is about 0.3-3%. It occurs in more than 50% of individuals with [[tuberous sclerosis]], often bilaterally.
==Gender==
Angiomyolipoma is twice as common in females as in males.
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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Latest revision as of 11:55, 6 November 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Faizan Sheraz, M.D. [3], Rekha, M.D.

Overview

The incidence of angiomyolipoma is approximately 30 per 100,000 individuals worldwide. Females are more commonly affected with angiomyolipoma than males. Angiomyolipoma commonly affects individuals older than 40 years of age.

Epidemiology and Demographics

Prevalence

Incidence

Gender

  • Females are more commonly affected with angiomyolipoma than males. The female to male ratio is approximately 4 to 1.

Age

References

  1. Rakowski SK, Winterkorn EB, Paul E, Steele DJ, Halpern EF, Thiele EA (2006). "Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors". Kidney Int. 70 (10): 1777–82. doi:10.1038/sj.ki.5001853. PMID 17003820.
  2. Rakowski SK, Winterkorn EB, Paul E, Steele DJ, Halpern EF, Thiele EA (2006). "Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors". Kidney Int. 70 (10): 1777–82. doi:10.1038/sj.ki.5001853. PMID 17003820.
  3. Bissler JJ, Kingswood JC (2004). "Renal angiomyolipomata". Kidney Int. 66 (3): 924–34. doi:10.1111/j.1523-1755.2004.00838.x. PMID 15327383.
  4. Koo KC, Kim WT, Ham WS, Lee JS, Ju HJ, Choi YD (2010). "Trends of presentation and clinical outcome of treated renal angiomyolipoma". Yonsei Med J. 51 (5): 728–34. doi:10.3349/ymj.2010.51.5.728. PMC 2908871. PMID 20635448.

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