Angiomyolipoma classification: Difference between revisions

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__NOTOC__
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{{Angiomyolipoma}}
{{Angiomyolipoma}}
{{CMG}}''' Associate Editor-In-Chief:''' {{CZ}}
{{CMG}}''' Associate Editor-In-Chief:''' {{CZ}}, {{Faizan}},{{Rekha}}


==Overview==
==Overview==
[[Angiomyolipoma]] may be classified according to [[Radiological|radiologic]] appearance into 7 subtypes: classic [[angiomyolipoma]], triphasic [[angiomyolipoma]], fat poor [[angiomyolipoma]], hyperattenuating [[angiomyolipoma]], isoattenuating [[angiomyolipoma]], [[angiomyolipoma]] with [[epithelial]] [[Cyst|cysts]], and [[angiomyolipoma]] in [[lymphangioleiomyomatosis]].<ref name="pmid24504542">{{cite journal| author=Jinzaki M, Silverman SG, Akita H, Nagashima Y, Mikami S, Oya M| title=Renal angiomyolipoma: a radiological classification and update on recent developments in diagnosis and management. | journal=Abdom Imaging | year= 2014 | volume= 39 | issue= 3 | pages= 588-604 | pmid=24504542 | doi=10.1007/s00261-014-0083-3 | pmc=PMC4040184 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24504542  }} </ref>


==Classification==
==Classification==
[[Angiomyolipoma]] may be classified according to [[World Health Organization]] ([[WHO]]) into as follows:<ref name="pmid24504542" /><ref name="pmid18635231">{{cite journal| author=Lane BR, Aydin H, Danforth TL, Zhou M, Remer EM, Novick AC et al.| title=Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid. | journal=J Urol | year= 2008 | volume= 180 | issue= 3 | pages= 836-43 | pmid=18635231 | doi=10.1016/j.juro.2008.05.041 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18635231  }}</ref><ref name="Park2017">{{cite journal|last1=Park|first1=Byung Kwan|title=Renal Angiomyolipoma: Radiologic Classification and Imaging Features According to the Amount of Fat|journal=American Journal of Roentgenology|volume=209|issue=4|year=2017|pages=826–835|issn=0361-803X|doi=10.2214/AJR.17.17973}}</ref><ref name="SilvermanMortele2007">{{cite journal|last1=Silverman|first1=Stuart G.|last2=Mortele|first2=Koenraad J.|last3=Tuncali|first3=Kemal|last4=Jinzaki|first4=Masahiro|last5=Cibas|first5=Edmund S.|title=Hyperattenuating Renal Masses: Etiologies, Pathogenesis, and Imaging Evaluation|journal=RadioGraphics|volume=27|issue=4|year=2007|pages=1131–1143|issn=0271-5333|doi=10.1148/rg.274065147}}</ref>


* Isolated Angiomyolipoma (80%)
 
** Angiomyolipoma is about 4 times more common in women than in men.
 
** Interestingly, 80% of the cases involve the right kidney.
 
* Angiomyolipoma associated with [[tuberous sclerosis]] (20%).
 
** Angiomyolipoma occurs in 80% patients with [[tuberous sclerosis]].
 
** Angiomyolipoma also occurs young women with lymphangiomyomatosis without other stigmata of [[tuberous sclerosis]]. Angiomyolipoma and lymphangiomyomatosis are sometimes considered ''the forme fruste'' of [[tuberous sclerosis]].
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align="center"
| valign="top" |
|+
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Radiologic Classification}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Features}}
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
Classic angiomyolipoma
| style="padding: 5px 5px; background: #F5F5F5;" |
*Abundant [[fat]]
*Fat [[tissue]] in renal sinus
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
Triphasic angiomyolipoma
| style="padding: 5px 5px; background: #F5F5F5;" |
*Mature [[adipose tissue]]
*Dysmorphic [[Blood vessel|blood vessels]]
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
Fat poor angiomyolipoma
| style="padding: 5px 5px; background: #F5F5F5;" |
*Minimal fat tissue
*Abundant [[smooth muscle]] component
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
Hyperattenuating angiomyolipoma
| style="padding: 5px 5px; background: #F5F5F5;" |
*Abundant smooth muscle component
*Hyperattenuating tissue
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
Isoattenuating angiomyolipoma
| style="padding: 5px 5px; background: #F5F5F5;" |
*Scattered fat tissue
*Smooth muscle component
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
Angiomyolipoma with epithelial cysts
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Epithelium]] lined [[Cyst|cysts]]
*Fat poor
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
Angiomyolipoma in lymphangioleiomyomatosis
| style="padding: 5px 5px; background: #F5F5F5;" |
*Atypical smooth muscle component
*[[Cystic]] changes
|}


==References==
==References==
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Latest revision as of 16:08, 4 November 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Faizan Sheraz, M.D. [3],Rekha, M.D.

Overview

Angiomyolipoma may be classified according to radiologic appearance into 7 subtypes: classic angiomyolipoma, triphasic angiomyolipoma, fat poor angiomyolipoma, hyperattenuating angiomyolipoma, isoattenuating angiomyolipoma, angiomyolipoma with epithelial cysts, and angiomyolipoma in lymphangioleiomyomatosis.[1]

Classification

Angiomyolipoma may be classified according to World Health Organization (WHO) into as follows:[1][2][3][4]




Radiologic Classification Features

Classic angiomyolipoma

Triphasic angiomyolipoma

Fat poor angiomyolipoma

Hyperattenuating angiomyolipoma

  • Abundant smooth muscle component
  • Hyperattenuating tissue

Isoattenuating angiomyolipoma

  • Scattered fat tissue
  • Smooth muscle component

Angiomyolipoma with epithelial cysts

Angiomyolipoma in lymphangioleiomyomatosis

  • Atypical smooth muscle component
  • Cystic changes

References

  1. ↑ 1.0 1.1 Jinzaki M, Silverman SG, Akita H, Nagashima Y, Mikami S, Oya M (2014). "Renal angiomyolipoma: a radiological classification and update on recent developments in diagnosis and management". Abdom Imaging. 39 (3): 588–604. doi:10.1007/s00261-014-0083-3. PMC 4040184. PMID 24504542.
  2. ↑ Lane BR, Aydin H, Danforth TL, Zhou M, Remer EM, Novick AC; et al. (2008). "Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid". J Urol. 180 (3): 836–43. doi:10.1016/j.juro.2008.05.041. PMID 18635231.
  3. ↑ Park, Byung Kwan (2017). "Renal Angiomyolipoma: Radiologic Classification and Imaging Features According to the Amount of Fat". American Journal of Roentgenology. 209 (4): 826–835. doi:10.2214/AJR.17.17973. ISSN 0361-803X.
  4. ↑ Silverman, Stuart G.; Mortele, Koenraad J.; Tuncali, Kemal; Jinzaki, Masahiro; Cibas, Edmund S. (2007). "Hyperattenuating Renal Masses: Etiologies, Pathogenesis, and Imaging Evaluation". RadioGraphics. 27 (4): 1131–1143. doi:10.1148/rg.274065147. ISSN 0271-5333.


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