Alprenolol: Difference between revisions
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{{Drugbox | {{Drugbox | ||
| verifiedrevid = 443660388 | | verifiedrevid = 443660388 | ||
| IUPAC_name = (''RS'')-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol | | IUPAC_name = (''RS'')-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol | ||
| image = Alprenolol2. | | image = Alprenolol2.png | ||
<!--Clinical data--> | <!--Clinical data--> | ||
| Line 60: | Line 59: | ||
}} | }} | ||
__NOTOC__ | __NOTOC__ | ||
{{CMG}} | {{CMG}}; {{AE}} {{SS}} | ||
{{SB}} Atenenol (Tsuruhara Seiyaku, Japan); Elp (Shyh Dar, Taiwan); Skajilol (Kotobuki Seiyaku, Japan) | |||
==Overview== | ==Overview== | ||
'''Alprenolol''', or '''alfeprol''', '''alpheprol''', and '''alprenololum''' ('''Gubernal''', '''Regletin''', '''Yobir''', '''Apllobal''', '''Aptine''', '''Aptol Duriles'''), is a non-selective [[beta blocker]] as well as [[5-HT1A_receptor|5-HT<sub>1A</sub> receptor]] [[receptor_antagonist|antagonist]], used in the treatment of [[angina pectoris]].<ref name="pmid4393977">{{cite journal |author=Hickie JB |title=Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial |journal=Med. J. Aust. |volume=2 |issue=6 |pages=268–72 |date=August 1970 |pmid=4393977 |doi= |url=}}</ref> It is no longer marketed by | '''Alprenolol''', or '''alfeprol''', '''alpheprol''', and '''alprenololum''' ('''Gubernal''', '''Regletin''', '''Yobir''', '''Apllobal''', '''Aptine''', '''Aptol Duriles'''), is a non-selective [[beta blocker]] as well as [[5-HT1A_receptor|5-HT<sub>1A</sub> receptor]] [[receptor_antagonist|antagonist]], used in the treatment of [[angina pectoris]].<ref name="pmid4393977">{{cite journal |author=Hickie JB |title=Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial |journal=Med. J. Aust. |volume=2 |issue=6 |pages=268–72 |date=August 1970 |pmid=4393977 |doi= |url=}}</ref> It is no longer marketed by AstraZeneca, but may still be available from other [[pharmaceutical_industry|pharmaceutical companies]] or [[generic drug|generically]]. | ||
==References== | ==References== | ||
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{{Beta blockers}} | {{Beta blockers}} | ||
[[Category:Cardiovascular Drugs]] | |||
[[Category:Drug]] | |||
[[Category:Beta blockers]] | [[Category:Beta blockers]] | ||
Latest revision as of 17:24, 18 August 2015
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| Clinical data | |
|---|---|
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral |
| ATC code | |
| Pharmacokinetic data | |
| Protein binding | 80% - 90% |
| Elimination half-life | 2-3 hours → 4-OH-alprenolol |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C15H23NO2 |
| Molar mass | 249.34 g/mol |
| 3D model (JSmol) | |
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| (verify) | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
Synonyms / Brand Names: Atenenol (Tsuruhara Seiyaku, Japan); Elp (Shyh Dar, Taiwan); Skajilol (Kotobuki Seiyaku, Japan)
Overview
Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as 5-HT1A receptor antagonist, used in the treatment of angina pectoris.[1] It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.