Adrenal carcinoma (patient information): Difference between revisions

Jump to navigation Jump to search
No edit summary
Line 5: Line 5:
{{CMG}}; {{AE}} {{S.M.}} {{AN}}
{{CMG}}; {{AE}} {{S.M.}} {{AN}}
==Overview==
==Overview==
Adrenocortical carcinoma is a cancer of the [[adrenal glands]].
[[Adrenocortical carcinoma]] is a [[cancer]] of the [[adrenal glands]].


==What are the symptoms of Adrenal carcinoma?==
==What are the symptoms of Adrenal carcinoma?==
Symptoms that suggest increased cortisol or other adrenal gland hormone production:
Fatty, rounded hump high on the back just below the neck (buffalo hump)
Flushed rounded face with pudgy cheeks (moon face)
Obesity
Stunted growth in height (short stature)
Virilization - the appearance of male characteristics, including increased body hair (especially on the face), pubic hair, acne, deepening of voice, and enlarged clitoris (girls)


Symptoms that suggest increased aldosterone production are the same as symptoms of low potassium and include:
* [[Symptoms]] that [[Suggestion|suggest]] increased [[cortisol]] or other [[adrenal gland]] [[hormone]] [[Product (biology)|production]]:
** [[Fat|Fatty]], rounded [[Buffalo hump|hump]] high on the [[back]] just below the [[neck]] ([[buffalo hump]])
** [[Flushing|Flushed]] rounded [[face]] with pudgy [[cheeks]] ([[moon face]])
** [[Obesity]]
** [[Stunted growth]] in [[Human height|height]] ([[short stature]])
** [[Virilization]] - the [[appearance]] of [[male]] [[Characteristic function (probability theory)|characteristics]], including increased [[body hair]] (especially on the [[face]]), [[pubic hair]], [[acne]], deepening of [[Human voice|voice]], and [[Clitoris enlargement|enlarged clitoris]] (girls)


Increased thirst
* [[Symptoms]] that [[Suggestion|suggest]] increased [[aldosterone]] [[Product (biology)|production]] are the same as [[symptoms]] of low [[potassium]] and include:
Muscle cramps
 
Urination
** Increased [[thirst]]
Weakness
** [[Muscle cramps]]
** [[Urination]]
** [[Weakness]]


==What causes Adrenal carcinoma?==
==What causes Adrenal carcinoma?==

Revision as of 19:26, 15 August 2019

Adrenal carcinoma

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for Adrenal carcinoma?

Prevention

What to expect (Outlook/Prognosis)?

Possible complications

Adrenal carcinoma On the Web

Ongoing Trials at Clinical Trials.gov

Images of Adrenal carcinoma

Videos on Adrenal carcinoma

FDA on Adrenal carcinoma

CDC on Adrenal carcinoma

Adrenal carcinoma in the news

Blogs on Adrenal carcinoma

Directions to Hospitals Treating Adrenal carcinoma

Risk calculators and risk factors for Adrenal carcinoma

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2] Aarti Narayan, M.B.B.S [3]

Overview

Adrenocortical carcinoma is a cancer of the adrenal glands.

What are the symptoms of Adrenal carcinoma?

What causes Adrenal carcinoma?

Adrenocortical carcinoma is most common in children younger than 5 and adults in their 30s and 40s.

Adrenocortical carcinoma may be linked to a cancer syndrome that is passed down through families (inherited). Both men and women can develop this tumor.

Adrenocortical carcinoma can produce the hormones cortisol, aldosterone, estrogen, or testosterone, as well as other hormones. In women the tumor often releases these hormones, which can lead to male characteristics.

The cause is unknown. About 2 people per million develop this type of tumor.

Diagnosis

A physical exam may reveal high blood pressure and changes in body shape, such as breast enlargement in men (gynecomastia) or male characteristics in women (virilization). Blood tests will be done to check hormone levels: ACTH level will be low. Aldosterone level will be high. Cortisol level will be high. Potassium level will be low.

Imaging tests may include:

Abdominal x-ray CT scan of the abdomen MRI of the abdomen

When to seek urgent medical care?

Call your health care provider if you or your child has symptoms of adrenocortical carcinoma, Cushing syndrome, or failure to grow.

Treatment options

Primary treatment is surgery to remove the tumor. Adrenocortical carcinoma may not improve with chemotherapy. Medications may be given to reduce production of cortisol, which causes many of the symptoms.

What to expect (Outlook/Prognosis)?

The outcome depends on how early the diagnosis is made and whether the tumor has spread (metastasized). Tumors that have spread usually lead to death within 1 to 3 years.

Possible complications

The tumor can spread to the liver, bone, lung, or other areas.

Sources

Template:WH Template:WS