Acute tubular necrosis laboratory findings: Difference between revisions

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==Laboratory Findings==
==Laboratory Findings==
* Complete blood count (CBC):
* [[Complete blood count]] ([[Complete blood count|CBC]]):
** Anaemia due to decreased erythropoietin production.
** [[Anemia|Anaemia]] may be  due to decreased [[erythropoietin]] production.
** Abnormal platelets
** Abnormal [[Platelet|platelets]]
* Urinalysis:<ref name="pmid19921458">{{cite journal |vauthors=Kanbay M, Kasapoglu B, Perazella MA |title=Acute tubular necrosis and pre-renal acute kidney injury: utility of urine microscopy in their evaluation- a systematic review |journal=Int Urol Nephrol |volume=42 |issue=2 |pages=425–33 |date=June 2010 |pmid=19921458 |doi=10.1007/s11255-009-9673-3 |url=}}</ref>
* [[Urinalysis]]:<ref name="pmid19921458">{{cite journal |vauthors=Kanbay M, Kasapoglu B, Perazella MA |title=Acute tubular necrosis and pre-renal acute kidney injury: utility of urine microscopy in their evaluation- a systematic review |journal=Int Urol Nephrol |volume=42 |issue=2 |pages=425–33 |date=June 2010 |pmid=19921458 |doi=10.1007/s11255-009-9673-3 |url=}}</ref>
** Urine sediment microscopy may show muddy brown granular casts or epithelial cell casts, and renal tubular epithelial cells.
** [[Urine]] sediment [[microscopy]] may show muddy brown granular casts or epithelial cell casts, and renal tubular epithelial cells.
** Urine sodium concentration:<ref name="pmid666184">{{cite journal |vauthors=Miller TR, Anderson RJ, Linas SL, Henrich WL, Berns AS, Gabow PA, Schrier RW |title=Urinary diagnostic indices in acute renal failure: a prospective study |journal=Ann. Intern. Med. |volume=89 |issue=1 |pages=47–50 |date=July 1978 |pmid=666184 |doi= |url=}}</ref> >40 mEq/L  
** [[Urine]] [[sodium]] concentration:<ref name="pmid666184">{{cite journal |vauthors=Miller TR, Anderson RJ, Linas SL, Henrich WL, Berns AS, Gabow PA, Schrier RW |title=Urinary diagnostic indices in acute renal failure: a prospective study |journal=Ann. Intern. Med. |volume=89 |issue=1 |pages=47–50 |date=July 1978 |pmid=666184 |doi= |url=}}</ref> >40 mEq/L  
** Urine fractional excretion of sodium concentration:<ref name="pmid6486145">{{cite journal |vauthors=Steiner RW |title=Interpreting the fractional excretion of sodium |journal=Am. J. Med. |volume=77 |issue=4 |pages=699–702 |date=October 1984 |pmid=6486145 |doi= |url=}}</ref> > 2%
** [[Urine]] [[Fractional sodium excretion|fractional excretion of sodium]] concentration:<ref name="pmid6486145">{{cite journal |vauthors=Steiner RW |title=Interpreting the fractional excretion of sodium |journal=Am. J. Med. |volume=77 |issue=4 |pages=699–702 |date=October 1984 |pmid=6486145 |doi= |url=}}</ref> > 2%
*** Limitations of the fractional excretion of sodium percent: Some conditions include, radio contrast media induced nephropathy, Acute tubular necrosis in the presence of cirrhosis and congestive heart failure, and rhabdomyolysis may have <1%.
*** Limitations of the [[Fractional sodium excretion|fractional excretion of sodium]] percent: Some conditions include, [[Contrast media|radio contrast media]] induced nephropathy, acute tubular necrosis in the presence of cirrhosis and congestive heart failure, and rhabdomyolysis may have <1%.
** Urine osmolarity:<ref name="pmid666184">{{cite journal |vauthors=Miller TR, Anderson RJ, Linas SL, Henrich WL, Berns AS, Gabow PA, Schrier RW |title=Urinary diagnostic indices in acute renal failure: a prospective study |journal=Ann. Intern. Med. |volume=89 |issue=1 |pages=47–50 |date=July 1978 |pmid=666184 |doi= |url=}}</ref> <350 mosmol/kg
** [[Urine]] [[osmolarity]]:<ref name="pmid666184">{{cite journal |vauthors=Miller TR, Anderson RJ, Linas SL, Henrich WL, Berns AS, Gabow PA, Schrier RW |title=Urinary diagnostic indices in acute renal failure: a prospective study |journal=Ann. Intern. Med. |volume=89 |issue=1 |pages=47–50 |date=July 1978 |pmid=666184 |doi= |url=}}</ref> <350 mosmol/kg


==References==
==References==

Revision as of 15:30, 4 May 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].

OR

Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

OR

[Test] is usually normal for patients with [disease name].

OR

Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

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There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

References

  1. ↑ Kanbay M, Kasapoglu B, Perazella MA (June 2010). "Acute tubular necrosis and pre-renal acute kidney injury: utility of urine microscopy in their evaluation- a systematic review". Int Urol Nephrol. 42 (2): 425–33. doi:10.1007/s11255-009-9673-3. PMID 19921458.
  2. ↑ 2.0 2.1 Miller TR, Anderson RJ, Linas SL, Henrich WL, Berns AS, Gabow PA, Schrier RW (July 1978). "Urinary diagnostic indices in acute renal failure: a prospective study". Ann. Intern. Med. 89 (1): 47–50. PMID 666184.
  3. ↑ Steiner RW (October 1984). "Interpreting the fractional excretion of sodium". Am. J. Med. 77 (4): 699–702. PMID 6486145.

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