Actinomycosis laboratory tests: Difference between revisions

	Actinomycosis Microchapters
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Overview
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Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
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Chest X Ray
CT
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NICE Guidance
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Blogs on Actinomycosis laboratory tests
to Hospitals Treating Actinomycosis
Risk calculators and risk factors for Actinomycosis laboratory tests

	Actinomycosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Actinomycosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Actinomycosis laboratory tests On the Web
Most recent articles
cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Actinomycosis laboratory tests All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Actinomycosis laboratory tests
CDC on Actinomycosis laboratory tests
Actinomycosis laboratory tests in the news
Blogs on Actinomycosis laboratory tests
to Hospitals Treating Actinomycosis
Risk calculators and risk factors for Actinomycosis laboratory tests

VisualWikitext

Latest revision as of 16:18, 18 September 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]Aditya Ganti M.B.B.S. [3]

Overview

The diagnosis of actinomycosis can be confirmed by either a positive bacterial culture or by histopathological identification.

Laboratory findings

The gold standard for diagnosing actinomycosis is the histological examination and bacterial culture. Other laboratory findings are non-specific and include^[1]^[2]

CBC

Anemia with mild leucocytosis
Elevated ESR, and CRP
Elevated alkaline phosphatase in hepatic actinomycosis

Culture

The isolation and identification of Actinomyces can confirm a diagnosis of actinomycosis.
Common clinical specimens employed in isolation are samples of pus from infected tissue.
Cultures are positive between the 7th and 21st day when grown anaerobically at 37°C.

Histopathology

Findings on microscopy that are supportive for diagnosing actinomycosis include:

Gram-positive
Filamentous organisms
Sulfur granules

Gallery

Actinomycosis bovis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis bovis. From Public Health Image Library (PHIL). ^[3]
Actinomyces sp. From Public Health Image Library (PHIL). ^[3]
Actinomyces sp. From Public Health Image Library (PHIL). ^[3]
Actinomyces sp. From Public Health Image Library (PHIL). ^[3]
Actinomyces sp. From Public Health Image Library (PHIL). ^[3]
Actinomyces sp. From Public Health Image Library (PHIL). ^[3]
Actinomyces sp. From Public Health Image Library (PHIL). ^[3]
Actinomycosis viscosus. From Public Health Image Library (PHIL). ^[3]
Actinomycosis viscosus. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis. From Public Health Image Library (PHIL). ^[3]
Actinomycosis naeslundi. From Public Health Image Library (PHIL). ^[3]
Actinomycosis naeslundi. From Public Health Image Library (PHIL). ^[3]
Actinomycosis naeslundi. From Public Health Image Library (PHIL). ^[3]
Actinomycosis naeslundi. From Public Health Image Library (PHIL). ^[3]

References

↑ Acevedo F, Baudrand R, Letelier LM, Gaete P (2008). "Actinomycosis: a great pretender. Case reports of unusual presentations and a review of the literature". Int. J. Infect. Dis. 12 (4): 358–62. doi:10.1016/j.ijid.2007.10.006. PMID 18164641.
↑ Mani RK, Mishra V, Singh PK, Pradhan D (2017). "Pulmonary actinomycosis: a clinical surprise!". BMJ Case Rep. 2017. doi:10.1136/bcr-2016-218959. PMID 28130291.
↑ ^3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 ^3.21 ^3.22 ^3.23 ^3.24 ^3.25 ^3.26 ^3.27 ^3.28 "Public Health Image Library (PHIL)".

Template:Bacterial diseases

de:Aktinomykose gl:Actinomicose hr:Aktinomikoza nl:Actinomycose sr:Актиномикоза fi:Aktinomykoosi uk:Актиномікоз

Template:WikiDoc Sources

[pmid18164641-1] Acevedo F, Baudrand R, Letelier LM, Gaete P (2008). "Actinomycosis: a great pretender. Case reports of unusual presentations and a review of the literature". Int. J. Infect. Dis. 12 (4): 358–62. doi:10.1016/j.ijid.2007.10.006. PMID 18164641.

[pmid28130291-2] Mani RK, Mishra V, Singh PK, Pradhan D (2017). "Pulmonary actinomycosis: a clinical surprise!". BMJ Case Rep. 2017. doi:10.1136/bcr-2016-218959. PMID 28130291.

[PHIL-3] 3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 ^3.21 ^3.22 ^3.23 ^3.24 ^3.25 ^3.26 ^3.27 ^3.28 "Public Health Image Library (PHIL)".

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[2]

[3]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Actinomycosis}}
-{{CMG}}; {{AE}} {{JH}}
+{{CMG}}; {{AE}} {{JH}}{{ADG}}
 ==Overview==
+The diagnosis of [[actinomycosis]] can be confirmed by either a positive [[Bacterial cultures|bacterial culture]] or by [[Histopathology|histopathological identification.]]
 ==Laboratory findings==
-The gold standard for diagnosing actinomycosis is histological examination and bacterial culture.<ref name="pmid18164641">{{cite journal |vauthors=Acevedo F, Baudrand R, Letelier LM, Gaete P |title=Actinomycosis: a great pretender. Case reports of unusual presentations and a review of the literature |journal=Int. J. Infect. Dis. |volume=12 |issue=4 |pages=358–62 |year=2008 |pmid=18164641 |doi=10.1016/j.ijid.2007.10.006 |url=}}</ref><ref name="pmid28130291">{{cite journal |vauthors=Mani RK, Mishra V, Singh PK, Pradhan D |title=Pulmonary actinomycosis: a clinical surprise! |journal=BMJ Case Rep |volume=2017 |issue= |pages= |year=2017 |pmid=28130291 |doi=10.1136/bcr-2016-218959 |url=}}</ref>
+The [[Gold standard (test)|gold standard]] for diagnosing actinomycosis is the [[histological]] examination and [[Microbiological culture|bacterial culture]]. Other laboratory findings are non-specific and include<ref name="pmid18164641">{{cite journal |vauthors=Acevedo F, Baudrand R, Letelier LM, Gaete P |title=Actinomycosis: a great pretender. Case reports of unusual presentations and a review of the literature |journal=Int. J. Infect. Dis. |volume=12 |issue=4 |pages=358–62 |year=2008 |pmid=18164641 |doi=10.1016/j.ijid.2007.10.006 |url=}}</ref><ref name="pmid28130291">{{cite journal |vauthors=Mani RK, Mishra V, Singh PK, Pradhan D |title=Pulmonary actinomycosis: a clinical surprise! |journal=BMJ Case Rep |volume=2017 |issue= |pages= |year=2017 |pmid=28130291 |doi=10.1136/bcr-2016-218959 |url=}}</ref>
 ===CBC===
-Findings are non-specific and include
+*[[Anemia]] with mild [[leucocytosis]]
-*Anemia with mild leucocytosis
+*Elevated [[ESR|ESR,]] and [[C-reactive protein|CRP]]
-*Elevated ESR, and CRP
+*Elevated [[alkaline phosphatase]] in [[hepatic]] actinomycosis
-*Elevated Alkaline phosphatase in hepatic actinomycosis
 ===Culture===
-*The isolation and identification of Actinomyces can confirm a diagnosis of Actinomycosis.
+*The isolation and identification of [[Actinomyces]] can confirm a diagnosis of [[Actinomycosis|actinomycosis.]]
-*The most common clinical specimens employed in isolation are samples of pus, tissue, or sulphur granules
+*Common clinical specimens employed in isolation are samples of [[pus]] from [[infected]] [[tissue]].
-*Cultures are positive between the 7th and 21st day when grown anaerobically at 37C.
+*Cultures are positive between the 7th and 21st day when grown [[Anaerobic organism|anaerobically]] at 37°C.
 ===Histopathology===
-*Demonstration of gram positive filamentous organisms and sulphur granules on histological examination is strongly supportive of a diagnosis of actinomycosis.
+Findings on microscopy that are supportive for diagnosing actinomycosis include:
-*Although the presence of sulphur granules is helpful in making the diagnosis, they are not always recovered in culture confirmed cases of actinomycosis.
+*[[Gram-positive]]
+*Filamentous [[organisms]]
+*Sulfur [[granules]]
 ==Gallery==
@@ Line 104: / Line 109: @@
 [[Category:Bacterial diseases]]
 [[Category:Disease]]
-[[Category:Infectious disease]]
 [[Category:Overview complete]]
 [[Category:Dermatology]]