Adenocarcinoma of the lung history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]

Overview

Common symptoms of adenocarcinoma of the lung include dyspnea, hemoptysis, chronic coughing, chest pain, cachexia, dysphonia, and symptoms arising fromparaneoplastic syndromes.

The majority of patients with [disease name] are asymptomatic.

OR

The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

• The majority of patients with [disease name] are asymptomatic.

OR

• The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
• Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 

History

Patients with adenocarcinoma of the lung may have a positive history of:

• Smoking
• Exposure to second-hand smoke
• Family history of lung cancer
• Exposure to high levels of air pollution
• Radiation therapy to the chest
• Expsure to radon gas
• Exposure to asbestos
• Exposure to high levels of arsenic in drinking water
• Occupational exposure to chemical carcinogens
• Previous lung disease
• Indoor burning of coal
• SLE

Common Symptoms

Common symptoms of adenocarcinoma of the lung include:

• Dyspnea
• Hemoptysis
• Chronic coughing
• Wheezing
• Chest pain
• Abdominal pain
• Cachexia
• Fatigue
• Loss of appetite
• Dysphonia

Less Common Symptoms

Less common and late symptoms of adenocarcinoma of the lung include:

• Bone pain
• Dysphagia
• Superior vena cava syndrome
• Neurological changes:

• Weakness
• Numbness in extremities
• Dizziness
• Seizure

• Lymphadenopathy
• Symptoms due to paraneoplastic syndromes:
  • Paraneoplastic syndrome is a group of symptoms that occurs when substances released by cancer cells affect the normal function of other organs or tissues.
  • Small cell lung cancer causes paraneoplastic syndromes more often than non–small cell lung cancer.
  • Paraneoplastic syndromes may present with adenocarcinoma of the lung include:
    • Hypercalcemia (more commonly seen in squamous cell lung cancer)
    • Weakness
    • Lack of coordination
    • Changes in mental function
    • High blood pressure
    • Nausea
    • Vomiting
    • Hypertrophic osteoarthropathy:
      • Increased and sometimes painful growth of some bones, especially fingertips
      • Finger clubbing
      • Pain and swelling of bones and joints

References

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