Hepatocellular carcinoma Echocardiography or Ultrasound
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]
Overview
On ultrasonography, changes in the liver contour and increased nodularity may be evident. The echo texture may appear coarse along with an increase in echogenecity from focal fatty changes and irregular appearing areas with fibrosis, fatty change, or calcifications.
Echocardiography
- Echocardiograms may be helpful in the measurement of ejection fraction and identification of ischemic and hypokinetic areas of the ventricles. This is useful in establishing a diagnosis of congestive cardiac failurebecause of the underlying cause of liver cirrhosis.
- Contrast echocardiography is a useful diagnostic test for hepatopulmonary syndrome:
- Intravenous microbubbles (> 10 micrometers in diameter) from agitated normal saline that are normally obstructed by pulmonary capillaries (normally <8 to 15 micrometers) rapidly transit the lung and appear in the left atrium of the heart within 7 heart beats.
- Intravenous technetium-99m–labeled albumin may transit the lungs and appear in the kidney and brain.
Ultrasound Findings
- Ultrasound may be helpful in the diagnosis of hepatocellular carcinoma. Findings on an ultrasound suggestive of hepatocellular carcinoma include:[1][2]
- Small hypoechoic lesion with poorly defined margins and coarse irregular internal echoes.
- When the tumor increases in size it appears heterogeneous with fibrosis, fatty change, or calcifications.
- Infiltrative HCC may be difficult to differentiate from background cirrhosis.
Contrast enhanced ultrasound
The following phases are noted on the contrast enhanced ultrasonography of hepatocellular carcinoma:[3]
Phases | Findings |
---|---|
Arterial Phase | Enhanced arteries due to neovascularity |
Portal Venous Phase | Weak echogenicity relative to the background liver is noted after the washout
Tumor thrombus may be visible |
References
- ↑ Malhi H, Grant EG, Duddalwar V (2014). "Contrast-enhanced ultrasound of the liver and kidney". Radiol. Clin. North Am. 52 (6): 1177–90. doi:10.1016/j.rcl.2014.07.005. PMID 25444099.
- ↑ "Hepatocellular Carcinoma - W. Y. Lau - Google Books".
- ↑ Malhi H, Grant EG, Duddalwar V (2014). "Contrast-enhanced ultrasound of the liver and kidney". Radiol. Clin. North Am. 52 (6): 1177–90. doi:10.1016/j.rcl.2014.07.005. PMID 25444099.