Primary biliary cirrhosis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]
Overview
The prevalence of primary biliary cirrhosis is approximately 19 to 402 cases per 100,000 individuals worldwide.[1][2]Primary biliary cirrhosis commonly affects individuals in their 40s or 50s.[3][4]There is no racial predilection to primary biliary cirrhosis. Females are more commonly affected by primary biliary cirrhosis than males.[5]The majority of primary biliary cirrhosis cases are reported in northern Europe and North America (particularly in Scandinavia, Great Britain, and the northern midwest regions of the United States).[6]
Epidemiology and Demographics
Prevalence
- The prevalence of primary biliary cirrhosis is approximately 19 to 402 cases per 100,000 individuals worldwide.[1][2]
Age
Race
- There is no racial predilection to primary biliary cirrhosis.
Gender
- Females are more commonly affected by primary biliary cirrhosis than males.[5]
Region
- The majority of primary biliary cirrhosis cases are reported in northern Europe and North America (particularly in Scandinavia, Great Britain, and the northern midwest regions of the United States).[6]
References
- ↑ 1.0 1.1 Kim WR, Lindor KD, Locke GR, Therneau TM, Homburger HA, Batts KP; et al. (2000). "Epidemiology and natural history of primary biliary cirrhosis in a US community". Gastroenterology. 119 (6): 1631–6. PMID 11113084.
- ↑ 2.0 2.1 Sood S, Gow PJ, Christie JM, Angus PW (2004). "Epidemiology of primary biliary cirrhosis in Victoria, Australia: high prevalence in migrant populations". Gastroenterology. 127 (2): 470–5. PMID 15300579.
- ↑ 3.0 3.1 Kaplan MM, Gershwin ME (2005). "Primary biliary cirrhosis". N Engl J Med. 353 (12): 1261–73. doi:10.1056/NEJMra043898. PMID 16177252.
- ↑ 4.0 4.1 Dahlan Y, Smith L, Simmonds D, Jewell LD, Wanless I, Heathcote EJ; et al. (2003). "Pediatric-onset primary biliary cirrhosis". Gastroenterology. 125 (5): 1476–9. PMID 14598264.
- ↑ 5.0 5.1 Lleo A, Battezzati PM, Selmi C, Gershwin ME, Podda M (2008). "Is autoimmunity a matter of sex?". Autoimmun Rev. 7 (8): 626–30. doi:10.1016/j.autrev.2008.06.009. PMID 18603021.
- ↑ 6.0 6.1 Selmi C, Bowlus CL, Gershwin ME, Coppel RL (2011). "Primary biliary cirrhosis". Lancet. 377 (9777): 1600–9. doi:10.1016/S0140-6736(10)61965-4. PMID 21529926.