Cytomegalovirus infection history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]

Overview

Primary infection in majority of patients have a mononucleosis like presentation. Patients with immunosuppression have symptoms related to the affected organ system. Retinitis presents with blurred vision and floaters. Colitis presents with abdominal pain and bloody diarrhea. Pneumonitis is usually asymptomatic. Neurologic infection presents with altered mental status and focal neurological deficits.

History and Symptoms

Presentation of patients with CMV infection differs with the organ system involved and is as follows: [1]

CMV Retintis

CMV Colitis

Colitis presents with the following symptoms:

CMV Esophagitis

Patients with cytomegalovirus esophagitis present with symptoms of:

CMV Encephalitis

Patients with cytomegalovirus encephalitis presents with:

CMV Ventriculoencephalitis

Patients with cytomegalovirus ventricluloencephalitis present:

  • Acute onset of symptoms with focal neurological deficits
  • Cranial nerve palsies
  • Nystagmus
  • Rapid progression to death

CMV Polyradiculomyelopathy

Patients with cytomegalovirus polyradiculomyelopathy present with features similar to Guillian Barre Syndrome and have symptoms such as:

References

  1. "www.idsociety.org" (PDF).