Cytomegalovirus infection physical examination
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The appearance of the patient depends on the stage of the disease. The patient may look very healthy or be ill-looking and cachectic. On fundus examination fluffy yellow-white retinal lesions, with or without intraretinal hemorrhages can be demonstrated in patients with CMV retinitis. Abdominal distension and tenderness can be present on examination in patients with CMV colitis. In patients with CMV encephalitis altered mental status and focal neurological deficits are present.
The appearance of the patient depends on the stage of the disease. The patient may look very healthy or be ill-looking and cachectic.
- Fluffy yellow-white retinal lesions, with or without intraretinal hemorrhage.
- Inflammation of the vitreous can be demonstrated in patients with severe immunosuppression.
- Blood vessels appear sheathed.
- If left untreated, retinitis is a rapidly progressive condition and on fundus examination it demonstrates a characteristic brushfire pattern, with a granular, white leading edge advancing before an atrophic gliotic scar.
- Abdominal tenderness
- Abdominal distension can be present on examination in patients with CMV colitis.
Central Nervous System
- Focal neurological deficits
- Altered mental status
- Normal or diminished deep tendon reflexes
- Zedtwitz-Liebenstein K, Diab-Elschahaw M, Frass M (2016). "Human Cytomegalovirus Infection in Nonimmunocompromised Patients: A Retrospective Analysis and Review of the Literature". Intervirology. 59 (3): 159–162. doi:10.1159/000454772. PMID 28095374.
- Luscalov S, Loga L, Dican L, Junie LM (2016). "Cytomegalovirus infection in immunosuppressed patients after kidney transplantation". Clujul Med. 89 (3): 343–6. doi:10.15386/cjmed-587. PMC 4990428. PMID 27547053.
- Khan TV, Toms C (2016). "Cytomegalovirus Colitis and Subsequent New Diagnosis of Inflammatory Bowel Disease in an Immunocompetent Host: A Case Study and Literature Review". Am J Case Rep. 17: 538–43. PMC 4968430. PMID 27460032.