Ulcerative colitis classification

Revision as of 21:08, 19 May 2017 by Usama Talib (talk | contribs)
Jump to navigation Jump to search

Ulcerative colitis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Ulcerative colitis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Abdominal X Ray

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Alternative Treatments

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Ulcerative colitis classification On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Ulcerative colitis classification

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Ulcerative colitis classification

CDC on Ulcerative colitis classification

Ulcerative colitis classification in the news

Blogs on Ulcerative colitis classification

Directions to Hospitals Treating Ulcerative colitis

Risk calculators and risk factors for Ulcerative colitis classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The inflammatory bowel disease (IBD) is divided primarily into ulcerative colitis and Crohn's disease. Some cases which depict overlapping features of both ulcerative colitis and Crohn's disease can be classified as intermediate colitis. Depending on the location of involved are with respect the descending colon, ulcerative colitis can be classified as proximal or distal. Based on the severity, ulcerative colitis can be classified into mild, moderate, severe or fulminant.[1]

Classification

The inflammatory bowel disease (IBD) is divided primarily into ulcerative colitis and Crohn's disease. Ulcerative colitis can be classified on the basis of location wit respect to the distal colon and on the bassi of severity.[1][2][3][4]

Classification of Ulcerate Colitis based on Location

Ulcerative colitis can be classified as follows based on the location of involvement of the colon:

  • Distal
    • Limited below the descending colon
    • Topical therapy can be used
  • Proximal
    • Extends proximal to the descending colon
    • Systemic therapy is required

Classification of Ulcerate Colitis based on Severity

  • Mild
    • < 4 loose stools per day (+/- blood)
    • No dehydration
    • Mild crampy pain
    • No fever
    • Normal hemoglobin
    • Normal ESR
  • Moderate
    • > 4 loose stools per day (+/- blood)
    • Mild dehydration
    • Abdominal pain that is not severe
    • Low grade fever
    • Mild anemia not requiring blood transfusions
  • Severe
    • ≥6 loose bloody stools per day
    • Moderate to severe dehydration
    • Severe abdominal cramps
    • High fever (temperature ≥37.5ºC)
    • HR ≥90 beats/minute
    • Hemoglobin <10.5 g/dL
    • Elevated ESR (≥30 mm/hour)
    • Rapid weight loss
  • Fulminant
    • >10 loose stools per day
    • Continuous bleeding
    • Severe dehydration
    • Severe abdominal pain
    • Abdominal distension
    • High fever (temperature ≥37.5ºC)
    • HR ≥90 beats/minute
    • Hemoglobin <10.5 g/dL
    • Elevated ESR (≥30 mm/hour)
    • Rapid weight loss

References

  1. 1.0 1.1 Kornbluth A, Sachar DB, Practice Parameters Committee of the American College of Gastroenterology (2010). "Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters Committee". Am J Gastroenterol. 105 (3): 501–23, quiz 524. doi:10.1038/ajg.2009.727. PMID 20068560.
  2. Zhao X, Zhou C, Ma J, Zhu Y, Sun M, Wang P; et al. (2017). "Efficacy and safety of rectal 5-aminosalicylic acid versus corticosteroids in active distal ulcerative colitis: a systematic review and network meta-analysis". Sci Rep. 7: 46693. doi:10.1038/srep46693. PMC 5404224. PMID 28440311.
  3. Fumery M, Dulai PS, Gupta S, Prokop LJ, Ramamoorthy S, Sandborn WJ; et al. (2017). "Incidence, Risk Factors, and Outcomes of Colorectal Cancer in Patients With Ulcerative Colitis With Low-Grade Dysplasia: A Systematic Review and Meta-analysis". Clin Gastroenterol Hepatol. 15 (5): 665–674.e5. doi:10.1016/j.cgh.2016.11.025. PMC 5401779. PMID 27916678.
  4. Tran DH, Wang J, Ha C, Ho W, Mattai SA, Oikonomopoulos A; et al. (2017). "Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn's disease, and clinical prognosis in inflammatory bowel disease". BMC Gastroenterol. 17 (1): 63. doi:10.1186/s12876-017-0619-4. PMC 5427565. PMID 28494754.

Template:WH Template:WS