Zollinger-Ellison syndrome medical therapy

Zollinger-Ellison syndrome Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

Pharmacologic medical therapies for Zollinger-Ellison syndrome include proton pump inhibitors, H2-receptor antagonists, Chemotherapy, and hormonal therapy.

Medical Therapy

Medical therapy for Zollinger-Ellison syndrome may includes the following:

• Proton pump inhibitors

• Omeprazole
• Lansoprazole)

• H2-receptor antagonists

• Famotidine
• Ranitidine)

• Chemotherapy

• Used for tumors that can not be surgically resected
• Streptozotocin
• 5-fluorouracil
• Doxorubicin

• Hormonal therapy

• Octreotide can be used to slow down acid secretion