Craniopharyngioma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]

Overview

The demographic patterns of craniopharyngioma are not well described because the tumor is rare. In addition, most cancer registries collect data only on malignant conditions and, therefore, they are not useful in the study of craniopharyngioma, considered to be of borderline histological malignancy. Incidence rates are similar in males and females and between Caucasians and African Americans. Tumors are more common among children of age 5 to 15 years and older adults of greater than 65 years,the lowest rates occur among those aged 15 to 34 years. Survival is highest for patients diagnosed at a younger age.

Epidemiology and demographics

Prevalence

The prevalence of craniopharyngioma in the United States is estimated to be 338 cases annually, with 96 occurring in children from 0 to 14 years of age.[1]

Incidence

The incidence of craniopharyngioma in the United States was estimated from two population-based cancer registries that include brain tumors of benign and borderline malignancy: the Central Brain Tumor Registry of the United States (CBTRUS) and the Los Angeles county Cancer Surveillance Program. Information on additional pediatric tumors was available from the Greater Delaware Valley Pediatric Tumor Registry (GDVPTR). The overall incidence of craniopharyngioma is 0.13 per 100,000 person years.[2]

Age

A bimodal distribution by age was noted with peak incidence rates in children (aged 5-14 years; more common) and among older adults (aged 65-74 years in CBTRUS and 50-74 years in Los Angeles county).[3]

Gender

There appears to be a similar incidence in both males and females.[4]

Race

No racial predilection is seen in craniopharyngioma cases.

References

  1. Incidence. Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM. Pubmed. http://www.ncbi.nlm.nih.gov/pubmed/9761047
  2. Incidence. Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM. Pubmed. http://www.ncbi.nlm.nih.gov/pubmed/9761047
  3. Incidence. Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM. Pubmed. http://www.ncbi.nlm.nih.gov/pubmed/9761047
  4. Epidemiology. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/craniopharyngioma


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