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|SubCategory=Pulmonology, General Principles, Infectious Disease
|SubCategory=Pulmonology, General Principles, Infectious Disease
|Prompt=A 7-year-old child is brought to his pediatrician by his mother for a 4 day history of increasingly severe cough.  On physical exam, the patient is febrile and in between fits of coughing, displays an inspiratory whoop.  The child immigrated from rural India with his family 2 years ago.  Which of the following media could be used to culture the causal organism?
|Prompt=A 7-year-old child is brought to his pediatrician by his mother for a 4 day history of increasingly severe cough.  On physical exam, the patient is febrile and in between fits of coughing, displays an inspiratory whoop.  The child immigrated from rural India with his family 2 years ago.  Which of the following media could be used to culture the causal organism?
|Explanation=The patient in this vignette is suffering from [[whooping cough]], an infection caused by the organism [[Bordetella pertussis]].  The patient’s immigration history suggests that he did not receive routine vaccinations, placing him at higher risk for whooping cough, a very rare infection in the US due to vaccination (part of DTaP vaccine).  [[Whooping cough]] is characterized by fits of paroxysmal coughing, and in 50% of patients an inspiratory “whoop” that can be appreciated as the patient attempts to draw air through a partially closed [[glottis]].  [[Bordetella pertussis]] is a [[gram negative[[, aerobic coccobaccilus which can be cultured on Bordet-Genou agar.
|Explanation=The patient in this vignette is suffering from [[whooping cough]], an infection caused by the organism [[Bordetella pertussis]].  The patient’s immigration history suggests that he did not receive routine vaccinations, placing him at higher risk for whooping cough, a very rare infection in the US due to vaccination (part of DTaP vaccine).  [[Whooping cough]] is characterized by fits of paroxysmal coughing, and in 50% of patients an inspiratory “whoop” that can be appreciated as the patient attempts to draw air through a partially closed [[glottis]].  [[Bordetella pertussis]] is a [[gram negative]], aerobic coccobaccilus which can be cultured on Bordet-Genou agar.
|AnswerA=Eaton’s Agar
|AnswerA=Eaton’s Agar
|AnswerAExp=Eaton’s agar is used to culture [[Mycoplasma pneumoniae]].
|AnswerAExp=Eaton’s agar is used to culture [[Mycoplasma pneumoniae]].

Revision as of 20:38, 15 March 2014

{{WBRQuestion |QuestionAuthor=William J Gibson |ExamType=USMLE Step 1 |MainCategory=Microbiology |SubCategory=Pulmonology, General Principles, Infectious Disease |MainCategory=Microbiology |SubCategory=Pulmonology, General Principles, Infectious Disease |MainCategory=Microbiology |SubCategory=Pulmonology, General Principles, Infectious Disease |MainCategory=Microbiology |MainCategory=Microbiology |SubCategory=Pulmonology, General Principles, Infectious Disease |MainCategory=Microbiology |SubCategory=Pulmonology, General Principles, Infectious Disease |MainCategory=Microbiology |SubCategory=Pulmonology, General Principles, Infectious Disease |MainCategory=Microbiology |SubCategory=Pulmonology, General Principles, Infectious Disease |MainCategory=Microbiology |MainCategory=Microbiology |SubCategory=Pulmonology, General Principles, Infectious Disease |Prompt=A 7-year-old child is brought to his pediatrician by his mother for a 4 day history of increasingly severe cough. On physical exam, the patient is febrile and in between fits of coughing, displays an inspiratory whoop. The child immigrated from rural India with his family 2 years ago. Which of the following media could be used to culture the causal organism? |Explanation=The patient in this vignette is suffering from whooping cough, an infection caused by the organism Bordetella pertussis. The patient’s immigration history suggests that he did not receive routine vaccinations, placing him at higher risk for whooping cough, a very rare infection in the US due to vaccination (part of DTaP vaccine). Whooping cough is characterized by fits of paroxysmal coughing, and in 50% of patients an inspiratory “whoop” that can be appreciated as the patient attempts to draw air through a partially closed glottis. Bordetella pertussis is a gram negative, aerobic coccobaccilus which can be cultured on Bordet-Genou agar. |AnswerA=Eaton’s Agar |AnswerAExp=Eaton’s agar is used to culture Mycoplasma pneumoniae. |AnswerB=Charcoal yeast extract |AnswerBExp=Charcoal yeast extract is used to culture Legionella pneumophila. |AnswerC=Tellurite agar |AnswerCExp=Tellurite agar is used to culture Corynebacterium diphtheriae. |AnswerD=Bordet-Genou agar |AnswerDExp=[[Bordetella pertussis] may be cultured on Bordet-Genou Agar. |AnswerE=Lowenstein-Jensen |AnswerEExp=Lowenstein-Jensen agar is used to culture Mycobacterium tuberculosis. |EducationalObjectives=Bordetella pertussis causes whopping cough and is cultured on Bordet-Genou agar. |References=First Aid 2014 page 122; First Aid 2012 page 148 |RightAnswer=D |WBRKeyword=MIcrobiology, Respiratory, Cough, Bacteria, Laboratory |Approved=Yes }}