Hydralazine injection adverse reactions: Difference between revisions
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==ADVERSE REACTIONS== | |||
Adverse reactions with hydralazine are usually reversible when dosage is reduced. However, in some cases it may be necessary to discontinue the drug. The following adverse reactions have been observed, but there has not been enough systematic collection of data to support an estimate of their frequency. | |||
===Common=== | |||
[[headache]], [[anorexia]], [[nausea]], vomiting, diarrhea, palpitations, tachycardia, angina pectoris. | |||
===Less Frequent=== | |||
====Digestive==== | |||
[[constipation]], [[paralytic ileus]]. | |||
====Cardiovascular==== | |||
[[hypotension]], paradoxical pressor response, [[edema]]. | |||
====Respiratory==== | |||
[[dyspnea]]. | |||
====Neurologic==== | |||
[[peripheral neuritis]], evidenced by [[paresthesia]], [[numbness]], and [[tingling]]; [[dizziness]]; [[tremors]]; [[muscle cramps]]; psychotic reactions characterized by [[depression]], [[disorientation]], or [[anxiety]]. | |||
====Genitourinary==== | |||
difficulty in [[urination]]. | |||
====Hematologic==== | |||
blood dyscrasias, consisting of reduction in hemoglobin and red cell count, [[leukopenia]], [[agranulocytosis]], [[purpura]]; [[lymphadenopathy]]; [[splenomegaly]]. | |||
====Hypersensitive Reactions==== | |||
[[rash]], [[urticaria]], [[pruritus]], [[fever]], [[chills]], [[arthralgia]], [[eosinophilia]], and rarely, [[hepatitis]]. | |||
====Other==== | |||
<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = HYDRALAZINE HYDROCHLORIDE INJECTION [FRESENIUS KABI USA, LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c3797028-c625-4f70-ae69-8a5f6f23f1b8 | publisher = | date = | accessdate = 10 March 2014 }}</ref> | nasal congestion, [[flushing]], [[lacrimation]], [[conjunctivitis]].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = HYDRALAZINE HYDROCHLORIDE INJECTION [FRESENIUS KABI USA, LLC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c3797028-c625-4f70-ae69-8a5f6f23f1b8 | publisher = | date = | accessdate = 10 March 2014 }}</ref> | ||
Revision as of 06:25, 11 March 2014
| Hydralazine |
|---|
| HYDRALAZINE tablet® FDA Package Insert |
| Indications and Usage |
| Dosage and Administration |
| Contraindications |
| Warnings |
| Precautions |
| Adverse Reactions |
| Drug Interactions |
| Use in Specific Populations |
| Overdosage |
| Description |
| Clinical Pharmacology |
| Nonclinical Toxicology |
| How Supplied/Storage and Handling |
| Labels and Packages |
| HYDRALAZINE injection® FDA Package Insert |
| Indications and Usage |
| Dosage and Administration |
| Contraindications |
| Warnings |
| Precautions |
| Adverse Reactions |
| Drug Interactions |
| Use in Specific Populations |
| Overdosage |
| Description |
| Clinical Pharmacology |
| Nonclinical Toxicology |
| How Supplied/Storage and Handling |
| Labels and Packages |
| Clinical Trials on Hydralazine |
| ClinicalTrials.gov |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]
ADVERSE REACTIONS
Adverse reactions with hydralazine are usually reversible when dosage is reduced. However, in some cases it may be necessary to discontinue the drug. The following adverse reactions have been observed, but there has not been enough systematic collection of data to support an estimate of their frequency.
Common
headache, anorexia, nausea, vomiting, diarrhea, palpitations, tachycardia, angina pectoris.
Less Frequent
Digestive
constipation, paralytic ileus.
Cardiovascular
hypotension, paradoxical pressor response, edema.
Respiratory
Neurologic
peripheral neuritis, evidenced by paresthesia, numbness, and tingling; dizziness; tremors; muscle cramps; psychotic reactions characterized by depression, disorientation, or anxiety.
Genitourinary
difficulty in urination.
Hematologic
blood dyscrasias, consisting of reduction in hemoglobin and red cell count, leukopenia, agranulocytosis, purpura; lymphadenopathy; splenomegaly.
Hypersensitive Reactions
rash, urticaria, pruritus, fever, chills, arthralgia, eosinophilia, and rarely, hepatitis.
Other
nasal congestion, flushing, lacrimation, conjunctivitis.[1]
References
- ↑ "HYDRALAZINE HYDROCHLORIDE INJECTION [FRESENIUS KABI USA, LLC]". Retrieved 10 March 2014.