Pyelonephritis medical therapy: Difference between revisions
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| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Fluoroquinolones]]'''''<br>'''''[[Ciprofloxacin]] 500 mg PO bid ×7 days<br>[[Levofloxacin]] 750 mg PO q24 × 5 days<br>[[Ofloxacin]] 400 mg Po bid<br>[[Moxifloxacin]] 400 mg PO q24h''''' | | style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Fluoroquinolones]]'''''<br>'''''[[Ciprofloxacin]] 500 mg PO bid ×7 days<br>[[Levofloxacin]] 750 mg PO q24 × 5 days<br>[[Ofloxacin]] 400 mg Po bid<br>[[Moxifloxacin]] 400 mg PO q24h''''' | ||
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! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Alternative Regimen(14 day regimen)'' | ! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Alternative Regimen(14 day regimen)'' | ||
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| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[TMP-SMX]] 160/800 mg PO bid'''''<br>OR<br>'''''▸ Oral[[β-lactam]]<br>[[Amoxicillin-clavulanate]] 875/125 mg po q12h or 500/125 mg po tid or 1000 /125 mg po bid <br>[[Cefdinir]] 300 mg po q12h or 600 mg po q24 <br>[[Cefaclor]] 250-500 mg po q8h<br>[[Cefpodoxime-proxetil]] 100-200 mg po q12h<br>[[Cephalexin]]250-500 mg po q6h not studied well but effective.''''' | | style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[TMP-SMX]] 160/800 mg PO bid'''''<br>OR<br>'''''▸ Oral[[β-lactam]]<br>[[Amoxicillin-clavulanate]] 875/125 mg po q12h or 500/125 mg po tid or 1000 /125 mg po bid <br>[[Cefdinir]] 300 mg po q12h or 600 mg po q24 <br>[[Cefaclor]] 250-500 mg po q8h<br>[[Cefpodoxime-proxetil]] 100-200 mg po q12h<br>[[Cephalexin]]250-500 mg po q6h not studied well but effective.''''' | ||
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As practically all cases of pyelonephritis are due to bacterial infections, [[antibiotic]]s are the mainstay of treatment. Mild cases may be treated with oral therapy, but generally [[intravenous]] antibiotics are required for the initial stages of treatment. The type of antibiotic depends on local practice, and may include [[fluoroquinolone]]s (e.g. [[ciprofloxacin]]), [[beta-lactam antibiotic]]s (e.g. [[amoxicillin]] or a [[cephalosporin]]), [[trimethoprim]] (or [[co-trimoxazole]]) or [[nitrofurantoin]]. [[Aminoglycoside]]s are avoided due to their toxicity, but may be added for a short duration. | As practically all cases of pyelonephritis are due to bacterial infections, [[antibiotic]]s are the mainstay of treatment. Mild cases may be treated with oral therapy, but generally [[intravenous]] antibiotics are required for the initial stages of treatment. The type of antibiotic depends on local practice, and may include [[fluoroquinolone]]s (e.g. [[ciprofloxacin]]), [[beta-lactam antibiotic]]s (e.g. [[amoxicillin]] or a [[cephalosporin]]), [[trimethoprim]] (or [[co-trimoxazole]]) or [[nitrofurantoin]]. [[Aminoglycoside]]s are avoided due to their toxicity, but may be added for a short duration. |
Revision as of 14:25, 17 January 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Medical Therapy
If the patient is unwell and septic, intravenous fluids may be administered to compensate for the reduced oral intake, insensible losses (due to the raised temperature) and vasodilation and to maximize urine output. References |