Cefpirome: Difference between revisions

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Cephalosporin, Fourth-Generation
Cephalosporin, Fourth-Generation
==Brand Names==
CEFROM<sup>®</sup>
==FDA Package Insert==
'''  [[Cefpirome description|Description]]'''
'''| [[Cefpirome clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Cefpirome microbiology|Microbiology]]'''
'''| [[Cefpirome indications and usage|Indications and Usage]]'''
'''| [[Cefpirome contraindications|Contraindications]]'''
'''| [[Cefpirome warnings and precautions|Warnings and Precautions]]'''
'''| [[Cefpirome adverse reactions|Adverse Reactions]]'''
'''| [[Cefpirome drug interactions|Drug Interactions]]'''
'''| [[Cefpirome overdosage|Overdosage]]'''
'''| [[Cefpirome clinical studies|Clinical Studies]]'''
'''| [[Cefpirome dosage and administration|Dosage and Administration]]'''
'''| [[Cefpirome how supplied|How Supplied]]'''
'''| [[Cefpirome labels and packages|Labels and Packages]]'''


==Mechanism of Action==
==Mechanism of Action==

Revision as of 14:55, 2 January 2014

Cefpirome
CEFROM® Package Insert
Composition
Properties
Indications
Microbiology
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Dosage and Administration
How Supplied

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cefpirome is a fourth-generation cephalosporin which is considered highly active against Gram-positive bacteria and Gram-negative bacteria including Pseudomonas aeruginosa. It is marketed under the brand name of CEFROM by Sanofi Aventis group India.

Category

Cephalosporin, Fourth-Generation

Brand Names

CEFROM®


FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages

Mechanism of Action

Cefpirome blocks bacterial cell wall synthesis by binding to penicillin binding proteins. Cefpirome (not available in the United States) and cefepime are fourth-generation cephalosporins which possess antibacterial activity against several fastidious Gram negative bacteria.

Spectrum of Bacterial Susceptibility and Resistance

Currently, Bacteroides fragilis, Enterococci, Pseudomonas spp. and Staphylococci are resistant to Cefpirome Sulfate, and some Haemophilus spp. and Pneumococci have developed resistance to Cefpirome Sulfate to varying degrees.[1]

References

  1. "Cefpirome Sulfate spectrum of bacterial susceptibility and Resistance" (PDF).