High density lipoprotein causes: Difference between revisions
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==Causes== | ==Causes== | ||
* HDL cholesterol is a positive [[cardiac risk factor]] | * HDL cholesterol is a positive [[cardiac risk factor]] | ||
*:* | *:* If HDL < 35 mg/dL | ||
*:* Total cholesterol to HDL ratio in > 5.0 (in men) | *:* Total cholesterol to HDL ratio in > 5.0 (in men) | ||
*:* Total cholesterol to HDL ratio in > 4.5 (in women) | *:* Total cholesterol to HDL ratio in > 4.5 (in women) | ||
* Negative cardiac risk factor if | * Negative cardiac risk factor if HDL > 60 mg/dL | ||
=== Decreased === | === Decreased === |
Revision as of 15:56, 15 April 2013
High Density Lipoprotein Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]
Causes
- HDL cholesterol is a positive cardiac risk factor
- If HDL < 35 mg/dL
- Total cholesterol to HDL ratio in > 5.0 (in men)
- Total cholesterol to HDL ratio in > 4.5 (in women)
- Negative cardiac risk factor if HDL > 60 mg/dL
Decreased
- Apolipoprotein deficiency: Hypoalphalipoproteinemia can be of three types.
- Impaired synthesis of apo A-1: apo A-1 deficiency, apo A-1/C-3 deficiency, apo A-1 structural variants
- Increased catabolism: familial HDL deficiency, Tangier disease
- Enzymatic changes: genetic, reduced activity of lipoprotein lipase, insulin resistance
- Diabetes Mellitus
- Drugs
- Liver disease
- Menopause
- Obesity
- Puberty in males
- Tangier Disease
- Uremia
Increased
- Drugs
- Moderate alcohol intake
- Regular aerobic exercise
- Weight loss