Anasarca: Difference between revisions

Jump to navigation Jump to search
Line 59: Line 59:
*[[Hypothyroidism]] (advanced untreated hypothyroidism)
*[[Hypothyroidism]] (advanced untreated hypothyroidism)
*Idiopathic [[edema]]
*Idiopathic [[edema]]
*Increased capillary permeability
*[[Increased capillary permeability]]
*Increased interstitial oncotic pressure
*Increased interstitial oncotic pressure
*[[Interleukin-2]] therapy
*[[Interleukin-2]] therapy
*[[Kwashiorkor]]
*[[Kwashiorkor]]
*Lymphatic obstruction usually cause localized limb edema unless very proximal
*Lymphatic obstruction usually cause localized limb [[edema]] unless very proximal
*[[Malnutrition]]
*[[Malnutrition]]
*[[Malignant ascites]] is usually associated with lower extremities edema
*[[Malignant ascites]] is usually associated with lower extremities edema
Line 86: Line 86:
*[[Tropical sprue]]
*[[Tropical sprue]]
*Venous obstruction usually causes localized edema in the limb
*Venous obstruction usually causes localized edema in the limb
*Water overload
*[[Water overload]]
*[[Yellow nail syndrome]]
*[[Yellow nail syndrome]]



Revision as of 16:28, 25 January 2009

Anasarca
ICD-10 R60.1
ICD-9 782.3

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

WikiDoc Resources for Anasarca

Articles

Most recent articles on Anasarca

Most cited articles on Anasarca

Review articles on Anasarca

Articles on Anasarca in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Anasarca

Images of Anasarca

Photos of Anasarca

Podcasts & MP3s on Anasarca

Videos on Anasarca

Evidence Based Medicine

Cochrane Collaboration on Anasarca

Bandolier on Anasarca

TRIP on Anasarca

Clinical Trials

Ongoing Trials on Anasarca at Clinical Trials.gov

Trial results on Anasarca

Clinical Trials on Anasarca at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Anasarca

NICE Guidance on Anasarca

NHS PRODIGY Guidance

FDA on Anasarca

CDC on Anasarca

Books

Books on Anasarca

News

Anasarca in the news

Be alerted to news on Anasarca

News trends on Anasarca

Commentary

Blogs on Anasarca

Definitions

Definitions of Anasarca

Patient Resources / Community

Patient resources on Anasarca

Discussion groups on Anasarca

Patient Handouts on Anasarca

Directions to Hospitals Treating Anasarca

Risk calculators and risk factors for Anasarca

Healthcare Provider Resources

Symptoms of Anasarca

Causes & Risk Factors for Anasarca

Diagnostic studies for Anasarca

Treatment of Anasarca

Continuing Medical Education (CME)

CME Programs on Anasarca

International

Anasarca en Espanol

Anasarca en Francais

Business

Anasarca in the Marketplace

Patents on Anasarca

Experimental / Informatics

List of terms related to Anasarca

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Synonyms and keywords: Generalized edema, leucophlegmatia

Overview

Anasarca is a medical symptom characterized by widespread swelling of the skin due to effusion of fluid into the extracellular space. Anasarca is often due to either congestive cardiac failure, liver failure (cirrhosis of the liver), renal failure/disease, or the other diseases listed below. Plant-derived anticancer chemotherapeutic agents, such as docetaxel, cause anasarca through a poorly understood capillary leak syndrome.

Complete Differential Diagnosis of the Causes of Anasarca:

(In alphabetical order)

Complete Differential Diagnosis of the Causes of Anasarca:

(By organ system)

Cardiovascular Cardiac tamponade ,

Constrictive pericarditis, Cor pulmonale, Dilated cardiomyopathy, Effusive-constrictive pericarditis, Heart failure, Hypertrophic cardiomyopathy, Restrictive cardiomyopathy, Tricuspid stenosis

Chemical / poisoning No underlying causes
Dermatologic No underlying causes
Drug Side Effect Calcium channel blockers, Diazoxide, Docetaxel, Estrogens

Fludrocortisone, Interleukin-2 therapy, Minoxidil, Nonsteroidal antiinflammatory drugs, Corticosteriods

Ear Nose Throat No underlying causes
Endocrine Corticosteriods
Environmental No underlying causes
Gastroenterologic Alcoholic liver disease , Autoimmune hepatitis, Chronic hepatitis B, Chronic hepatitis C, Hepatic cirrhosis, Hepatic venous obstruction, Hereditary hemochromatosis, Portal thrombosis, Primary biliary cirrhosis, Primary sclerosing cholangitis, Wilson's disease
Genetic Angioedema, Alpha-1-antitrypsin deficiency, Hereditary angioedema

Hereditary hemochromatosis, Hypertrophic cardiomyopathy, Wilson's disease, Yellow nail syndrome

Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease Tropical sprue
Musculoskeletal / Ortho No underlying causes
Neurologic No underlying causes
Nutritional / Metabolic Hypoalbuminemia, Hypoproteinaemia, Kwashiorkor, Malnutrition

Protein loss, Protein-losing enteropathy, Reduced albumin synthesis, Refeeding edema, Sodium overload, Tropical sprue, Water overload

Obstetric/Gynecologic Eclampsia, Estrogens, Haemolytic disease of the newborn, Ovarian hyperstimulation syndrome, Pregnancy
Oncologic Malignant ascites
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Haemolytic disease of the newborn, Autoimmune hepatitis
Sexual No underlying causes
Trauma Trauma
Urologic No underlying causes
Miscellaneous No underlying causes



Treatment

The treatment of anasraca depends on the underlying cause. It involves the use of diuretics in cases related to heart failure or kidney disease. The latter may require hemodialysis especially if there are signs or symptoms of uremia. In cases of severe burns resulting in hypoalbuminemia and capillary leak, admission to a burn unit, volume and electrolyte replacement, and adequate nutrition is of paramount. Withdrawal of the offending drug is critical in drug-induced anasarca. The use of diuretics, paracentesis, and adequate nutritional supplementation is needed in anasarca secondary to hepatic cirrhosis. Profound hypothyroidism requires thyroid hormone replacement. Protein malabsorption syndromes require the identification of the underlying disease process and adequate protein supplementation.

Template:SIB Template:WH Template:WS