Epileptic Heart: Difference between revisions
| Line 6: | Line 6: | ||
Chronic epileptic episodes and the subsequent catecholamine surges and hypoxia events may affect the heart and coronary vessels and result in the dysfunction of the heart, this condition has known as the epileptic heart. This concept first described by Dr. Richard L. Verrier and his colleagues in 2020. | Chronic epileptic episodes and the subsequent catecholamine surges and hypoxia events may affect the heart and coronary vessels and result in the dysfunction of the heart, this condition has known as the epileptic heart. This concept first described by Dr. Richard L. Verrier and his colleagues in 2020. | ||
==Historical Perspective== | ==Historical Perspective== | ||
*The epileptic heart was first | * The Absence of [[cardiac]] activity during [[epilepsy]], first described by Dr. A.E.Russell, an English physician, in 1906.<ref name="Russell1906">{{cite journal|last1=Russell|first1=A.E.|title=CESSATION OF THE PULSE DURING THE ONSET OF EPILEPTIC FITS,|journal=The Lancet|volume=168|issue=4325|year=1906|pages=152–154|issn=01406736|doi=10.1016/S0140-6736(01)30477-4}}</ref> | ||
*The epileptic heart was first discribed by Dr. Richard L. Verrier and his colleagues, in 2020.<ref name="VerrierPang2020">{{cite journal|last1=Verrier|first1=Richard L.|last2=Pang|first2=Trudy D.|last3=Nearing|first3=Bruce D.|last4=Schachter|first4=Steven C.|title=The Epileptic Heart: Concept and clinical evidence|journal=Epilepsy & Behavior|volume=105|year=2020|pages=106946|issn=15255050|doi=10.1016/j.yebeh.2020.106946}}</ref> | |||
==Pathophysiology== | ==Pathophysiology== | ||
The exact mechanisms involved in the epileptic heart is still should be elucidated. However, the algorithm below provides beneficial information on the development of heart disease in the context of epilepsy.<ref name="VerrierSchachter2018">{{cite journal|last1=Verrier|first1=Richard L.|last2=Schachter|first2=Steven C.|title=Is heart disease in chronic epilepsy a consequence of seizures or a fellow traveler?|journal=Epilepsy & Behavior|volume=86|year=2018|pages=211–213|issn=15255050|doi=10.1016/j.yebeh.2018.06.027}}</ref> | The exact mechanisms involved in the epileptic heart is still should be elucidated. However, the algorithm below provides beneficial information on the development of heart disease in the context of epilepsy.<ref name="VerrierSchachter2018">{{cite journal|last1=Verrier|first1=Richard L.|last2=Schachter|first2=Steven C.|title=Is heart disease in chronic epilepsy a consequence of seizures or a fellow traveler?|journal=Epilepsy & Behavior|volume=86|year=2018|pages=211–213|issn=15255050|doi=10.1016/j.yebeh.2018.06.027}}</ref> | ||
Revision as of 02:24, 10 January 2021
|
WikiDoc Resources for Epileptic Heart |
|
Articles |
|---|
|
Most recent articles on Epileptic Heart Most cited articles on Epileptic Heart |
|
Media |
|
Powerpoint slides on Epileptic Heart |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on Epileptic Heart at Clinical Trials.gov Trial results on Epileptic Heart Clinical Trials on Epileptic Heart at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on Epileptic Heart NICE Guidance on Epileptic Heart
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Patient resources on Epileptic Heart Discussion groups on Epileptic Heart Patient Handouts on Epileptic Heart Directions to Hospitals Treating Epileptic Heart Risk calculators and risk factors for Epileptic Heart
|
|
Healthcare Provider Resources |
|
Causes & Risk Factors for Epileptic Heart |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Chronic epileptic episodes and the subsequent catecholamine surges and hypoxia events may affect the heart and coronary vessels and result in the dysfunction of the heart, this condition has known as the epileptic heart. This concept first described by Dr. Richard L. Verrier and his colleagues in 2020.
Historical Perspective
- The Absence of cardiac activity during epilepsy, first described by Dr. A.E.Russell, an English physician, in 1906.[1]
- The epileptic heart was first discribed by Dr. Richard L. Verrier and his colleagues, in 2020.[2]
Pathophysiology
The exact mechanisms involved in the epileptic heart is still should be elucidated. However, the algorithm below provides beneficial information on the development of heart disease in the context of epilepsy.[3]
| Epilepsy | |||||||||||||||||||||||||||||||||||||||
| Cardiac effects | |||||||||||||||||||||||||||||||||||||||
| Repeated hypoxia and subsequent myocardial ischemia | Cathecholamines-induced cardiotoxicity | ||||||||||||||||||||||||||||||||||||||
| Accelerated atherosclerosis | Myocardial stunning | Vacuolization of myocytes and fibrosis | |||||||||||||||||||||||||||||||||||||
References
- ↑ Russell, A.E. (1906). "CESSATION OF THE PULSE DURING THE ONSET OF EPILEPTIC FITS,". The Lancet. 168 (4325): 152–154. doi:10.1016/S0140-6736(01)30477-4. ISSN 0140-6736.
- ↑ Verrier, Richard L.; Pang, Trudy D.; Nearing, Bruce D.; Schachter, Steven C. (2020). "The Epileptic Heart: Concept and clinical evidence". Epilepsy & Behavior. 105: 106946. doi:10.1016/j.yebeh.2020.106946. ISSN 1525-5050.
- ↑ Verrier, Richard L.; Schachter, Steven C. (2018). "Is heart disease in chronic epilepsy a consequence of seizures or a fellow traveler?". Epilepsy & Behavior. 86: 211–213. doi:10.1016/j.yebeh.2018.06.027. ISSN 1525-5050.