Cowden syndrome screening: Difference between revisions
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**Starting at the age of <nowiki/>30-35 years, annua<nowiki/>l [[uterine]] [[biopsies]] should be considered. | **Starting at the age of <nowiki/>30-35 years, annua<nowiki/>l [[uterine]] [[biopsies]] should be considered. | ||
*[[Colon cancer|'''Colon cancer''']] | *[[Colon cancer|'''Colon cancer''']] | ||
**Startin<nowiki/>g at the age of <nowiki/>35<nowiki/> years, for ever<nowiki/>y 5 years [[colonoscopy]] should be considered. | **Startin<nowiki/>g at the age of <nowiki/>35<nowiki/> years, for ever<nowiki/>y 5 years [[colonoscopy]] should be considered.<ref name="pmid22672595">{{cite journal |vauthors=Nieuwenhuis MH, Kets CM, Murphy-Ryan M, Colas C, Möller P, Hes FJ, Hodgson SV, Olderode-Berends MJ, Aretz S, Heinimann K, Gomez Garcia EB, Douglas F, Spigelman A, Timshel S, Lindor NM, Vasen HF |title=Is colorectal surveillance indicated in patients with PTEN mutations? |journal=Colorectal Dis |volume=14 |issue=9 |pages=e562–6 |date=September 2012 |pmid=22672595 |doi=10.1111/j.1463-1318.2012.03121.x |url=}}</ref> | ||
*'''[[Thyroid cancer]]''' | *'''[[Thyroid cancer]]''' | ||
**Patie<nowiki/>nts at all ages sh<nowiki/><nowiki/>ould consider an a<nowiki/>nnual [[thyroid]] examination with an [[ultrasound scan]] is recommended.<ref name="pmid10594284">{{cite journal |vauthors=Harach HR, Soubeyran I, Brown A, Bonneau D, Longy M |title=Thyroid pathologic findings in patients with Cowden disease |journal=Ann Diagn Pathol |volume=3 |issue=6 |pages=331–40 |date=December 1999 |pmid=10594284 |doi=10.1053/ADPA00300331 |url=}}</ref><ref name="pmid21190448">{{cite journal |vauthors=Laury AR, Bongiovanni M, Tille JC, Kozakewich H, Nosé V |title=Thyroid pathology in PTEN-hamartoma tumor syndrome: characteristic findings of a distinct entity |journal=Thyroid |volume=21 |issue=2 |pages=135–44 |date=February 2011 |pmid=21190448 |doi=10.1089/thy.2010.0226 |url=}}</ref><ref name="pmid3698331">{{cite journal |vauthors=Starink TM, van der Veen JP, Arwert F, de Waal LP, de Lange GG, Gille JJ, Eriksson AW |title=The Cowden syndrome: a clinical and genetic study in 21 patients |journal=Clin. Genet. |volume=29 |issue=3 |pages=222–33 |date=March 1986 |pmid=3698331 |doi= |url=}}</ref><ref name="pmid22431287">{{cite journal |vauthors=Hall JE, Abdollahian DJ, Sinard RJ |title=Thyroid disease associated with Cowden syndrome: A meta-analysis |journal=Head Neck |volume=35 |issue=8 |pages=1189–94 |date=August 2013 |pmid=22431287 |doi=10.1002/hed.22971 |url=}}</ref> | **Patie<nowiki/>nts at all ages sh<nowiki/><nowiki/>ould consider an a<nowiki/>nnual [[thyroid]] examination with an [[ultrasound scan]] is recommended.<ref name="pmid10594284">{{cite journal |vauthors=Harach HR, Soubeyran I, Brown A, Bonneau D, Longy M |title=Thyroid pathologic findings in patients with Cowden disease |journal=Ann Diagn Pathol |volume=3 |issue=6 |pages=331–40 |date=December 1999 |pmid=10594284 |doi=10.1053/ADPA00300331 |url=}}</ref><ref name="pmid21190448">{{cite journal |vauthors=Laury AR, Bongiovanni M, Tille JC, Kozakewich H, Nosé V |title=Thyroid pathology in PTEN-hamartoma tumor syndrome: characteristic findings of a distinct entity |journal=Thyroid |volume=21 |issue=2 |pages=135–44 |date=February 2011 |pmid=21190448 |doi=10.1089/thy.2010.0226 |url=}}</ref><ref name="pmid3698331">{{cite journal |vauthors=Starink TM, van der Veen JP, Arwert F, de Waal LP, de Lange GG, Gille JJ, Eriksson AW |title=The Cowden syndrome: a clinical and genetic study in 21 patients |journal=Clin. Genet. |volume=29 |issue=3 |pages=222–33 |date=March 1986 |pmid=3698331 |doi= |url=}}</ref><ref name="pmid22431287">{{cite journal |vauthors=Hall JE, Abdollahian DJ, Sinard RJ |title=Thyroid disease associated with Cowden syndrome: A meta-analysis |journal=Head Neck |volume=35 |issue=8 |pages=1189–94 |date=August 2013 |pmid=22431287 |doi=10.1002/hed.22971 |url=}}</ref> | ||
Revision as of 17:32, 27 February 2019
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Cowden syndrome Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Cowden syndrome screening On the Web |
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American Roentgen Ray Society Images of Cowden syndrome screening |
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Risk calculators and risk factors for Cowden syndrome screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
According to the National Comprehensive Cancer Network (NCCN) Guidelines, screening for cowden syndrome patients is recommended for women who are at risk for breast cancer, uterine cancer and colon cancer.
Screening
According to the National Comprehensive Cancer Network (NCCN) Guidelines, screening for cowden syndrome patients is recommended for women who are at risk for:
- Breast cancer
- Starting at the age of 25 years, breast exam should be considered for every 6-12 months.[1][2]
- Starting at the age of 30-35 years, patients should consider magnetic resonance imaging (MRI) and and mammogram.
- Patients who are at risk for breast cancer also should consider 3D mammography.
- Uterine cancer
- Colon cancer
- Starting at the age of 35 years, for every 5 years colonoscopy should be considered.[3]
- Thyroid cancer
References
- ↑ FitzGerald MG, Marsh DJ, Wahrer D, Bell D, Caron S, Shannon KE, Ishioka C, Isselbacher KJ, Garber JE, Eng C, Haber DA (August 1998). "Germline mutations in PTEN are an infrequent cause of genetic predisposition to breast cancer". Oncogene. 17 (6): 727–31. doi:10.1038/sj.onc.1201984. PMID 9715274.
- ↑ Tung N, Battelli C, Allen B, Kaldate R, Bhatnagar S, Bowles K, Timms K, Garber JE, Herold C, Ellisen L, Krejdovsky J, DeLeonardis K, Sedgwick K, Soltis K, Roa B, Wenstrup RJ, Hartman AR (January 2015). "Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel". Cancer. 121 (1): 25–33. doi:10.1002/cncr.29010. PMID 25186627.
- ↑ Nieuwenhuis MH, Kets CM, Murphy-Ryan M, Colas C, Möller P, Hes FJ, Hodgson SV, Olderode-Berends MJ, Aretz S, Heinimann K, Gomez Garcia EB, Douglas F, Spigelman A, Timshel S, Lindor NM, Vasen HF (September 2012). "Is colorectal surveillance indicated in patients with PTEN mutations?". Colorectal Dis. 14 (9): e562–6. doi:10.1111/j.1463-1318.2012.03121.x. PMID 22672595.
- ↑ Harach HR, Soubeyran I, Brown A, Bonneau D, Longy M (December 1999). "Thyroid pathologic findings in patients with Cowden disease". Ann Diagn Pathol. 3 (6): 331–40. doi:10.1053/ADPA00300331. PMID 10594284.
- ↑ Laury AR, Bongiovanni M, Tille JC, Kozakewich H, Nosé V (February 2011). "Thyroid pathology in PTEN-hamartoma tumor syndrome: characteristic findings of a distinct entity". Thyroid. 21 (2): 135–44. doi:10.1089/thy.2010.0226. PMID 21190448.
- ↑ Starink TM, van der Veen JP, Arwert F, de Waal LP, de Lange GG, Gille JJ, Eriksson AW (March 1986). "The Cowden syndrome: a clinical and genetic study in 21 patients". Clin. Genet. 29 (3): 222–33. PMID 3698331.
- ↑ Hall JE, Abdollahian DJ, Sinard RJ (August 2013). "Thyroid disease associated with Cowden syndrome: A meta-analysis". Head Neck. 35 (8): 1189–94. doi:10.1002/hed.22971. PMID 22431287.