Cytomegalovirus infection history and symptoms: Difference between revisions

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==Overview==
==Overview==
Primary infection in majority of patients have a mononucleosis like presentation. Patients with immunosuppression have symptoms related to the affected organ system. Retinitis presents with blurred vision and floaters. Colitis presents with abdominal pain and bloody diarrhea. Pneumonitis is usually asymptomatic. Neurologic infection presents with altered mental status and focal neurological deficits.
Primary infection in majority of patients have a [[mononucleosis]] like presentation. Patients with [[immunosuppression]] have symptoms related to the affected organ system. [[Retinitis]] presents with [[blurred vision]] and [[floaters]]. [[Colitis]] presents with [[abdominal pain]] and [[bloody diarrhea]]. [[Pneumonitis]] is usually asymptomatic. Neurologic infection presents with [[altered mental status]] and focal neurological deficits.


==History and Symptoms==
==History and Symptoms==
Presentation of patients with CMV infection differs with the organ system involved and is as follows: <ref name="urlwww.idsociety.org">{{cite web |url=https://www.idsociety.org/uploadedFiles/HIVMA/Guidelines_Patient_Care/HIVMA_Standards_Practice_Guidelines/HIV_Guidelines/Guidelines_Content/adult_oi.pdf |title=www.idsociety.org |format= |work= |accessdate=}}</ref>
Presentation of patients with [[Cytomegalovirus infection|CMV infection]] differs with the organ system involved and is as follows: <ref name="urlwww.idsociety.org">{{cite web |url=https://www.idsociety.org/uploadedFiles/HIVMA/Guidelines_Patient_Care/HIVMA_Standards_Practice_Guidelines/HIV_Guidelines/Guidelines_Content/adult_oi.pdf |title=www.idsociety.org |format= |work= |accessdate=}}</ref>
===CMV Retintis===
===CMV Retintis===
*Peripheral retinitis can be asymptomatic or present with the following symptoms:  
*Peripheral [[retinitis]] can be asymptomatic or present with the following symptoms:  
**Floaters
**[[Floaters]]
**Scotomata
**[[Scotoma|Scotomata]]
**Peripheral visual field defects
**Peripheral [[Visual field defect|visual field defects]]
*Central retinal lesions or lesions impinging on the macula or optic nerve are result in decreased visual acuity and central field defects.
*Central retinal lesions or lesions impinging on the [[macula]] or [[optic nerve]] are result in decreased [[visual acuity]] and central field defects.
===CMV Colitis===
===CMV Colitis===
Colitis presents with the following symptoms:  
[[Colitis]] presents with the following symptoms:  
*Weight loss
*[[Weight loss]]
*Anorexia
*[[Anorexia]]
*Abdominal pain
*[[Abdominal pain]]
*Diarrhea
*[[Diarrhea]]
*Fever
*[[Fever]]
*Malaise
*[[Malaise]]
*Patients with perforation of the bowel present with acute abdominal pain.
*Patients with [[perforation]] of the [[bowel]] present with acute [[abdominal pain]].


===CMV Esophagitis===
===CMV Esophagitis===
Patients with cytomegalovirus esophagitis present with symptoms of:
Patients with [[cytomegalovirus]] [[esophagitis]] present with symptoms of:
*Odynophagia
*[[Odynophagia]]
*Nausea
*[[Nausea]]
*Mid-epigastric or retrosternal discomfort
*Mid-epigastric or retrosternal discomfort
*Fever
*[[Fever]]
===CMV Encephalitis===
===CMV Encephalitis===
Patients with cytomegalovirus encephalitis presents with:
Patients with [[cytomegalovirus]] [[encephalitis]] presents with:
*Fever
*[[Fever]]
*Lethargy  
*[[Lethargy]]
*Confusion
*[[Confusion]]


===CMV Ventriculoencephalitis===
===CMV Ventriculoencephalitis===
Patients with cytomegalovirus ventricluloencephalitis present:  
Patients with [[cytomegalovirus]] [[Encephalitis|ventricluloencephalitis]] present:  
*Acute onset of symptoms with focal neurological deficits
*Acute onset of symptoms with focal neurological deficits
*Cranial nerve palsies
*[[Cranial nerve]] palsies
*Nystagmus  
*[[Nystagmus]]
*Rapid progression to death
*Rapid progression to death


===CMV Polyradiculomyelopathy===
===CMV Polyradiculomyelopathy===
Patients with cytomegalovirus polyradiculomyelopathy present with features similar to Guillian Barre Syndrome and have symptoms such as:
Patients with [[cytomegalovirus]] [[Myelopathy|polyradiculomyelopathy]] present with features similar to [[Gullian-Barre syndrome|Guillian Barre Syndrome]] and have symptoms such as:
*Bladder incontinence
*[[Bladder incontinence]]
*Paraplegia with gradual worsening of symptoms over weeks
*[[Paraplegia]] with gradual worsening of symptoms over weeks


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 17:48, 30 May 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]

Overview

Primary infection in majority of patients have a mononucleosis like presentation. Patients with immunosuppression have symptoms related to the affected organ system. Retinitis presents with blurred vision and floaters. Colitis presents with abdominal pain and bloody diarrhea. Pneumonitis is usually asymptomatic. Neurologic infection presents with altered mental status and focal neurological deficits.

History and Symptoms

Presentation of patients with CMV infection differs with the organ system involved and is as follows: [1]

CMV Retintis

CMV Colitis

Colitis presents with the following symptoms:

CMV Esophagitis

Patients with cytomegalovirus esophagitis present with symptoms of:

CMV Encephalitis

Patients with cytomegalovirus encephalitis presents with:

CMV Ventriculoencephalitis

Patients with cytomegalovirus ventricluloencephalitis present:

  • Acute onset of symptoms with focal neurological deficits
  • Cranial nerve palsies
  • Nystagmus
  • Rapid progression to death

CMV Polyradiculomyelopathy

Patients with cytomegalovirus polyradiculomyelopathy present with features similar to Guillian Barre Syndrome and have symptoms such as:

References

  1. "www.idsociety.org" (PDF).