Bacterial meningitis other diagnostic studies: Difference between revisions

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Other diagnostic tests which may be used to diagnose bacterial meningitis may include:  
Other diagnostic tests which may be used to diagnose bacterial meningitis may include:  
===Rapid tests===
===Rapid tests===
Two rapid detection tests which may be used to diagnose bacterial meningitis may include:<br><ref name="pmid15494903">{{cite journal| author=Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM et al.| title=Practice guidelines for the management of bacterial meningitis. | journal=Clin Infect Dis | year= 2004 | volume= 39 | issue= 9 | pages= 1267-84 | pmid=15494903 | doi=10.1086/425368 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15494903  }} </ref><ref name="pmid16371872">{{cite journal| author=Saha SK, Darmstadt GL, Yamanaka N, Billal DS, Nasreen T, Islam M et al.| title=Rapid diagnosis of pneumococcal meningitis: implications for treatment and measuring disease burden. | journal=Pediatr Infect Dis J | year= 2005 | volume= 24 | issue= 12 | pages= 1093-8 | pmid=16371872 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16371872  }} </ref><ref name="pmid18260752">{{cite journal| author=Werno AM, Murdoch DR| title=Medical microbiology: laboratory diagnosis of invasive pneumococcal disease. | journal=Clin Infect Dis | year= 2008 | volume= 46 | issue= 6 | pages= 926-32 | pmid=18260752 | doi=10.1086/528798 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18260752  }} </ref>
Two rapid detection tests which may be used to diagnose bacterial meningitis may include:<br><ref name="pmid15494903">{{cite journal| author=Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM et al.| title=Practice guidelines for the management of bacterial meningitis. | journal=Clin Infect Dis | year= 2004 | volume= 39 | issue= 9 | pages= 1267-84 | pmid=15494903 | doi=10.1086/425368 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15494903  }} </ref><ref name="pmid16371872">{{cite journal| author=Saha SK, Darmstadt GL, Yamanaka N, Billal DS, Nasreen T, Islam M et al.| title=Rapid diagnosis of pneumococcal meningitis: implications for treatment and measuring disease burden. | journal=Pediatr Infect Dis J | year= 2005 | volume= 24 | issue= 12 | pages= 1093-8 | pmid=16371872 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16371872  }} </ref><ref name="pmid18260752">{{cite journal| author=Werno AM, Murdoch DR| title=Medical microbiology: laboratory diagnosis of invasive pneumococcal disease. | journal=Clin Infect Dis | year= 2008 | volume= 46 | issue= 6 | pages= 926-32 | pmid=18260752 | doi=10.1086/528798 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18260752  }} </ref><br>
 
'''Latex agglutination test'''<br>
'''Latex agglutination test'''<br>
*May be used for detecting common meningeal pathogens<ref name="pmid15494903">{{cite journal| author=Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM et al.| title=Practice guidelines for the management of bacterial meningitis. | journal=Clin Infect Dis | year= 2004 | volume= 39 | issue= 9 | pages= 1267-84 | pmid=15494903 | doi=10.1086/425368 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15494903  }} </ref>  
*May be used for detecting common meningeal pathogens<ref name="pmid15494903">{{cite journal| author=Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM et al.| title=Practice guidelines for the management of bacterial meningitis. | journal=Clin Infect Dis | year= 2004 | volume= 39 | issue= 9 | pages= 1267-84 | pmid=15494903 | doi=10.1086/425368 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15494903  }} </ref>  

Revision as of 22:30, 9 January 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Overview

Other diagnostic tests

Other diagnostic tests which may be used to diagnose bacterial meningitis may include:

Rapid tests

Two rapid detection tests which may be used to diagnose bacterial meningitis may include:
[1][2][3]

Latex agglutination test

  • May be used for detecting common meningeal pathogens[1]
  • Not used routinely due to false positive results

Immunochromatographic tests

  • It is 100 percent sensitive and specific for diagnosing streptococcus pneumoniae infection.[2][3]

Nucleic acid amplification tests(NAT)

  • NAT such as PCR may be used to diagnose specific pathogen responsible for meningitis.
  • The sensitivity and specificity of PCR for pneumococcal meningitis is 92 percent and 100 percent respectively.
  • False positive tests may be reported with NAT.

References

  1. 1.0 1.1 Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM; et al. (2004). "Practice guidelines for the management of bacterial meningitis". Clin Infect Dis. 39 (9): 1267–84. doi:10.1086/425368. PMID 15494903.
  2. 2.0 2.1 Saha SK, Darmstadt GL, Yamanaka N, Billal DS, Nasreen T, Islam M; et al. (2005). "Rapid diagnosis of pneumococcal meningitis: implications for treatment and measuring disease burden". Pediatr Infect Dis J. 24 (12): 1093–8. PMID 16371872.
  3. 3.0 3.1 Werno AM, Murdoch DR (2008). "Medical microbiology: laboratory diagnosis of invasive pneumococcal disease". Clin Infect Dis. 46 (6): 926–32. doi:10.1086/528798. PMID 18260752.


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