Retinoblastoma differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
Retinoblastoma must be differentiated from other diseases that cause [[leukocoria]], such as [[congenital]] [[cataract]], persistent fetal vasculature, [[Coats disease]], | Retinoblastoma must be differentiated from other diseases that cause [[leukocoria]], such as [[congenital]] [[cataract]], persistent fetal vasculature, [[Coats disease]], [[coloboma]] of [[choroid]] or [[optic disc]], [[toxocariasis]], [[astrocytic]] [[hamartoma]], [[retinopathy of prematurity]], [[vitreous hemorrhage]], [[uveitis]], [[retinal dysplasia]], and [[medulloepithelioma]].<ref name="wiki"> Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma#cite_note-30 Accessed on October 2 2015</ref> | ||
==Differential diagnosis== | ==Differential diagnosis== | ||
Retinoblastoma must be differentiated from other diseases that cause [[leukocoria]]. The common causes of leukocoria in children include:<ref name="wiki"> Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma#cite_note-30 Accessed on October 2 2015</ref> | Retinoblastoma must be differentiated from other diseases that cause [[leukocoria]]. The common causes of leukocoria in children include:<ref name="wiki"> Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma#cite_note-30 Accessed on October 2 2015</ref> | ||
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*[[Coats disease]] | *[[Coats disease]] | ||
Less common causes of leukocoria include: | Less common causes of leukocoria include: | ||
*Coloboma of [[choroid]] or [[optic disc]] | *[[Coloboma]] of [[choroid]] or [[optic disc]] | ||
*[[Toxocariasis]] | *[[Toxocariasis]] | ||
*[[Astrocytic ]][[hamartoma]] | *[[Astrocytic ]][[hamartoma]] |
Revision as of 19:05, 16 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Retinoblastoma must be differentiated from other diseases that cause leukocoria, such as congenital cataract, persistent fetal vasculature, Coats disease, coloboma of choroid or optic disc, toxocariasis, astrocytic hamartoma, retinopathy of prematurity, vitreous hemorrhage, uveitis, retinal dysplasia, and medulloepithelioma.[1]
Differential diagnosis
Retinoblastoma must be differentiated from other diseases that cause leukocoria. The common causes of leukocoria in children include:[1]
- Congenital cataract
- Persistent fetal vasculature
- Coats disease
Less common causes of leukocoria include:
- Coloboma of choroid or optic disc
- Toxocariasis
- Astrocytic hamartoma
- Retinopathy of prematurity (stage 4, 5)
- Vitreous hemorrhage
- Uveitis
Differentiating features of some common and less common differential diagnosis are:
Disease/Condition | Differentiating Signs/Symptoms | Differentiating Tests |
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Congenital Cataract |
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Coats disease (exudative retinitis or retinal telangiectasis) |
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Persistent fetal vasculature (formerly known as persistent hyperplastic primary vitreous) |
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Retinopathy of prematurity (ROP) |
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Ocular toxocariasis |
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References
- ↑ 1.0 1.1 Retinoblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Retinoblastoma#cite_note-30 Accessed on October 2 2015