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Leukocoria refers to an abnormal white hue of the retina when viewed through routine medical ophthalmoscopy.


Usually, when a light is shone through the iris, the retina appears red to the observer. In leukocoria, the retina abnormally appears white. This may indicate congential cataracts, retrolental fibroplasia, corneal scarring, retinoblastoma, ocular toxocariasis, persistence of the tunica vasculosa lentis (PFV/PHPV), or Coats' disease, Norrie Disease, etc. Because of the potential life threatening nature of retinoblastoma, that condition is usually considered in the evaluation of leukocoria.

Physical Examination


Leukocoria (Retinoblastoma)[1]

The term is also sometimes spelled leukokoria.[2] In British English the usual spelling is leucocoria.[3]


  1. http://picasaweb.google.com/mcmumbi/USMLEIIImages
  2. thefreedictionary.com
  3. Demirci H et al. Leucocoria as the presenting sign of a ciliary body melanoma in a child. Br J Ophthalmol 2001;85:115-6. PMID 11201946.

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