Middle East respiratory syndrome coronavirus infection chest x ray: Difference between revisions
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==Overview== | ==Overview== | ||
[[MERS|Middle East Respiratory Syndrome]] ([[MERS]]) is a [[viral]] [[respiratory disease|respiratory illness]]. It is caused by an emerging [[coronavirus]], specifically a ''betacoronavirus'' called [[Middle east respiratory syndrome coronavirus|MERS-CoV]] ([[Middle east respiratory syndrome coronavirus|Middle East Respiratory Syndrome Coronavirus]]), first discovered in 2012. Being a relatively novel [[virus]], there is no [[virus]]-specific [[prevention]] or treatment options for [[MERS]] patients. Attending to the fact that a [[vaccine]] hasn't been developed yet, enhancing [[infection]] prevention and control measures is critical to prevent the possible spread of [[MERS-CoV]] in hospitals and communities. Persons with [[symptoms]] suspicious of [[MERS-CoV]] [[infection]] need medical evaluation. According to the [[CDC]]: a certified case of [[MERS-CoV]] [[infection]] is considered an individual who shows laboratory confirmation of [[infection]] by [[MERS-CoV]]. This last one is given by a positive [[PCR]] test of ≥2 specific genomic targets or, a single positive target followed by successful sequencing of a second; while a probable case of [[MERS-CoV]] [[infection]] is an individual who has missing or inconclusive laboratory test results for the [[infection]] and that has been in close contact with another individual who is a "laboratory-confirmed case" of [[MERS-CoV]] [[infection]]. In [[MERS-CoV]] [[infection]], [[chest radiograph]] typically shows [[alveolar]] changes ranging from unilateral [[lobar]] infiltration to bilateral diffuse involvement consistent with [[acute respiratory distress syndrome|acute respiratory distress syndrome (ARDS)]].<ref name="pmid24841273">{{cite journal| author=Dyall J, Coleman CM, Hart BJ, Venkataraman T, Holbrook MR, Kindrachuk J et al.| title=Repurposing of clinically developed drugs for treatment of Middle East Respiratory Coronavirus Infection. | journal=Antimicrob Agents Chemother | year= 2014 | volume= | issue= | pages= | pmid=24841273 | doi=10.1128/AAC.03036-14 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24841273 }} </ref><ref name=WHO>{{cite web | title = Clinical management of severe acute respiratory infections when novel coronavirus is suspected: What to do and what not to do | url = http://www.who.int/csr/disease/coronavirus_infections/InterimGuidance_ClinicalManagement_NovelCoronavirus_11Feb13u.pdf }}</ref><ref name=CDC>{{cite web | title = MERS Prevention and Treatment | url = http://www.cdc.gov/coronavirus/MERS/about/prevention.html }}</ref><ref name=CDC case definitions>{{cite web | title = Middle East Respiratory Syndrome (MERS) | url = http://www.cdc.gov/coronavirus/mers/case-def.html }}</ref> | |||
In [[MERS-CoV]] [[infection]], [[chest radiograph]] typically shows [[alveolar]] changes ranging from unilateral [[lobar]] infiltration to bilateral diffuse involvement consistent with [[acute respiratory distress syndrome|acute respiratory distress syndrome (ARDS)]]. | |||
==Chest X Ray== | ==Chest X Ray== |
Revision as of 03:01, 20 June 2014
Middle East Respiratory Syndrome Coronavirus Infection Microchapters |
Differentiating Middle East Respiratory Syndrome Coronavirus Infection from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Middle East respiratory syndrome coronavirus infection chest x ray On the Web |
American Roentgen Ray Society Images of Middle East respiratory syndrome coronavirus infection chest x ray |
FDA on Middle East respiratory syndrome coronavirus infection chest x ray |
CDC on Middle East respiratory syndrome coronavirus infection chest x ray |
Middle East respiratory syndrome coronavirus infection chest x ray in the news |
Blogs on Middle East respiratory syndrome coronavirus infection chest x ray |
Directions to Hospitals Treating Middle East respiratory syndrome coronavirus infection |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Middle East Respiratory Syndrome (MERS) is a viral respiratory illness. It is caused by an emerging coronavirus, specifically a betacoronavirus called MERS-CoV (Middle East Respiratory Syndrome Coronavirus), first discovered in 2012. Being a relatively novel virus, there is no virus-specific prevention or treatment options for MERS patients. Attending to the fact that a vaccine hasn't been developed yet, enhancing infection prevention and control measures is critical to prevent the possible spread of MERS-CoV in hospitals and communities. Persons with symptoms suspicious of MERS-CoV infection need medical evaluation. According to the CDC: a certified case of MERS-CoV infection is considered an individual who shows laboratory confirmation of infection by MERS-CoV. This last one is given by a positive PCR test of ≥2 specific genomic targets or, a single positive target followed by successful sequencing of a second; while a probable case of MERS-CoV infection is an individual who has missing or inconclusive laboratory test results for the infection and that has been in close contact with another individual who is a "laboratory-confirmed case" of MERS-CoV infection. In MERS-CoV infection, chest radiograph typically shows alveolar changes ranging from unilateral lobar infiltration to bilateral diffuse involvement consistent with acute respiratory distress syndrome (ARDS).[1][2][3]
Chest X Ray
MERS-CoV infection causes atypical pneumonia characterized by diffuse alveolar damage with the potential to progress to ARDS.[4] Chest X ray findings may range from focal to extensive abnormalities including:[5]
- Basal pleural thickening
- Bronchial wall thickening
- Pulmonary consolidation
- Increased bronchovascular markings
- Interstitial changes
- Patchy infiltrates
- Pleural effusions
- Reticulo-nodular airspace opacities
- Total opacification of lung segments and lobes
References
- ↑ Dyall J, Coleman CM, Hart BJ, Venkataraman T, Holbrook MR, Kindrachuk J; et al. (2014). "Repurposing of clinically developed drugs for treatment of Middle East Respiratory Coronavirus Infection". Antimicrob Agents Chemother. doi:10.1128/AAC.03036-14. PMID 24841273.
- ↑ "Clinical management of severe acute respiratory infections when novel coronavirus is suspected: What to do and what not to do" (PDF).
- ↑ "MERS Prevention and Treatment".
- ↑ Arabi, Yaseen M (2014-03-18). "Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection". Annals of internal medicine. 160 (6): 389–397. doi:10.7326/M13-2486. ISSN 1539-3704. PMID 24474051. Unknown parameter
|coauthors=
ignored (help) - ↑ Assiri, Abdullah (2013-09). "Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study". The Lancet infectious diseases. 13 (9): 752–761. doi:10.1016/S1473-3099(13)70204-4. ISSN 1474-4457. PMID 23891402. Unknown parameter
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