Melanoma classification: Difference between revisions
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*Most common subtype | *Most common subtype | ||
*Usually affects sun exposed sites among both men and women aged 50-70 years | *Usually affects sun exposed sites among both men and women aged 50-70 years | ||
*Characterized by presence of abundant junctional intraepidermal spread of malignant melanocytes | *Characterized by ''presence'' of abundant junctional intraepidermal spread of malignant melanocytes | ||
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|Nodular melanoma||15-25%|| | |Nodular melanoma||15-25%|| | ||
*Second most common subtype | *Second most common subtype | ||
*Usually affects sun exposed sites among both men and women aged 50-70 years | *Usually affects sun exposed sites among both men and women aged 50-70 years | ||
*Characterized by absence of junctional intraepidermal spread of malignant melanocytes | *Characterized by ''absence'' of junctional intraepidermal spread of malignant melanocytes | ||
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|Acral lentiginous melanoma||5%|| | |Acral lentiginous melanoma||5%|| | ||
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*Preceded by lentigo maligna | *Preceded by lentigo maligna | ||
*Common among elderly Caucasian patients | *Common among elderly Caucasian patients | ||
*Usually appears as a flat, non-palpable lesion that affects sun exposed sites, especially the head and neck (extremities less common) | *Usually appears as a flat, non-palpable lesion that affects sun exposed sites, especially the head and neck (extremities are less common) | ||
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| Non-cutaneous melanoma||5%|| | | Non-cutaneous melanoma||5%|| | ||
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| Desmoplastic/Spindle cell melanoma||Rare|| | | Desmoplastic/Spindle cell melanoma||Rare|| | ||
*Lesion typically amelanotic | *Lesion typically amelanotic and has a morphology similar to a scar tissue | ||
*Appears indolent but is highly infiltrative | *Appears indolent but is highly infiltrative | ||
*Characterized by local recurrence and perineural spread | *Characterized by local recurrence and perineural spread |
Revision as of 05:46, 22 August 2015
Melanoma Microchapters |
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Melanoma classification On the Web |
American Roentgen Ray Society Images of Melanoma classification |
Risk calculators and risk factors for Melanoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.
Overview
Melanoma may be classified into either cutaneous or subcutaneous melanomas. The most common 4 subtypes of cutaneous melanoma include superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Less common subtypes of melanoma include desmoplastic/spindle cell melanoma, nevoid melanoma, spitzoid melanocytic melanoma, angiotropic melanoma, blue nevus-like melanoma, and composite melanoma.
Classification of Melanoma
Shown below is a table that demonstrates that various subclasses of melanoma:[1][2]
Subtype | Frequency | Clinical Features |
Common Subtypes | ||
Superficial spreading melanoma | 70% |
|
Nodular melanoma | 15-25% |
|
Acral lentiginous melanoma | 5% |
|
Lentigo maligna melanoma | 1-5% |
|
Non-cutaneous melanoma | 5% |
|
Less Common Subtypes | ||
Desmoplastic/Spindle cell melanoma | Rare |
|
Nevoid melanoma | Rare |
|
Spitzoid melanocytic neoplasm | Rare |
|
Angiotropic melanoma | Rare |
|
Blue nevus-like melanoma | Rare |
|
Composite melanoma | Rare |
|