Sick sinus syndrome natural history, complications and prognosis: Difference between revisions
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{{Sick sinus syndrome}} | {{Sick sinus syndrome}} | ||
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==Overview== | ==Overview== | ||
Sick sinus syndrome natural history progress over decades. [[Patients]] are usually asymptomatic at first, but then [[symptoms]] may present due to the insufficient blood supply. Sinus pause or severe [[bradycardia]] may present with the [[central nervous system]] (CNS) under perfusion which manifests with [[presyncope]] or [[syncope]]. Possible [[complications]] of sick sinus syndrome include [[Cerebrovascular event|cerebrovascular events]], [[stroke]], [[Transient ischemic attack|transient ischemic events]], [[renal]], [[gastrointestinal]] hypo-perfusion, [[thromboembolism]], [[Fatigue]] and exercise intolerance. The syndrome is progressive, which means it usually gets worse over time. | |||
==Natural History, Complications and Prognosis== | ==Natural History, Complications and Prognosis== | ||
===Natural History=== | |||
* Sick sinus syndrome natural history progress over decades.<ref name="pmid913143">{{cite journal| author=Lien WP, Lee YS, Chang FZ, Lee SY, Chen CM, Tsai HC| title=The sick sinus syndrome: natural history of dysfunction of the sinoatrial node. | journal=Chest | year= 1977 | volume= 72 | issue= 5 | pages= 628-34 | pmid=913143 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=913143 }} </ref> | |||
* [[Patients]] are usually asymptomatic at first, but then [[symptoms]] may present due to the insufficient blood supply. | |||
* Sinus pause or severe [[bradycardia]] may present with the [[central nervous system]] ([[CNS]]) under perfusion which manifests with [[presyncope]] or [[syncope]]. | |||
===Complications=== | ===Complications=== | ||
* [[ | Possible [[complications]] of sick sinus syndrome include:<ref name="RubensteinSchulman1972">{{cite journal|last1=Rubenstein|first1=Joel J.|last2=Schulman|first2=Charles L.|last3=Yurchak|first3=Peter M.|last4=Desanctis|first4=Roman W.|title=Clinical Spectrum of the Sick Sinus Syndrome|journal=Circulation|volume=46|issue=1|year=1972|pages=5–13|issn=0009-7322|doi=10.1161/01.CIR.46.1.5}}</ref> | ||
* | *[[Cerebrovascular events]], [[stroke]], [[Transient ischemic attack|transient ischemic events]] | ||
* [[ | *[[Renal]] hypoperfusion may result in oliguria. | ||
* | *[[Gastrointestinal]] hypoperfusion which may present with [[abdominal pain]]. | ||
* [[ | *[[Thromboembolism]] | ||
*[[Fatigue]] and [[exercise intolerance]] | |||
===Prognosis=== | ===Prognosis=== | ||
* The syndrome is progressive, which means it usually gets worse over time. | * The syndrome is progressive, which means it usually gets worse over time.<ref name="pmid2403955">{{cite journal| author=Rodriguez RD, Schocken DD| title=Update on sick sinus syndrome, a cardiac disorder of aging. | journal=Geriatrics | year= 1990 | volume= 45 | issue= 1 | pages= 26-30, 33-6 | pmid=2403955 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2403955 }} </ref> | ||
* The long-term outlook is excellent for people who have a [[permanent pacemaker]] implanted. | * The long-term outlook is excellent for people who have a [[permanent pacemaker]] implanted. | ||
* The long-term progression of SSS is mostly related to the presence and severity of associated coronary or hypertensive [[cardiac disease]]. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Crowdiagnosis]] | |||
[[Category:Electrophysiology]] | |||
[[Category:Syndromes]] | |||
[[Category:Cardiology]] | |||
[[Category:Arrhythmia]] | |||
[[Category:Up-To-Date]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
Latest revision as of 16:11, 1 April 2020
Sick sinus syndrome Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Sahar Memar Montazerin, M.D.[2]
Overview
Sick sinus syndrome natural history progress over decades. Patients are usually asymptomatic at first, but then symptoms may present due to the insufficient blood supply. Sinus pause or severe bradycardia may present with the central nervous system (CNS) under perfusion which manifests with presyncope or syncope. Possible complications of sick sinus syndrome include cerebrovascular events, stroke, transient ischemic events, renal, gastrointestinal hypo-perfusion, thromboembolism, Fatigue and exercise intolerance. The syndrome is progressive, which means it usually gets worse over time.
Natural History, Complications and Prognosis
Natural History
- Sick sinus syndrome natural history progress over decades.[1]
- Patients are usually asymptomatic at first, but then symptoms may present due to the insufficient blood supply.
- Sinus pause or severe bradycardia may present with the central nervous system (CNS) under perfusion which manifests with presyncope or syncope.
Complications
Possible complications of sick sinus syndrome include:[2]
- Cerebrovascular events, stroke, transient ischemic events
- Renal hypoperfusion may result in oliguria.
- Gastrointestinal hypoperfusion which may present with abdominal pain.
- Thromboembolism
- Fatigue and exercise intolerance
Prognosis
- The syndrome is progressive, which means it usually gets worse over time.[3]
- The long-term outlook is excellent for people who have a permanent pacemaker implanted.
- The long-term progression of SSS is mostly related to the presence and severity of associated coronary or hypertensive cardiac disease.
References
- ↑ Lien WP, Lee YS, Chang FZ, Lee SY, Chen CM, Tsai HC (1977). "The sick sinus syndrome: natural history of dysfunction of the sinoatrial node". Chest. 72 (5): 628–34. PMID 913143.
- ↑ Rubenstein, Joel J.; Schulman, Charles L.; Yurchak, Peter M.; Desanctis, Roman W. (1972). "Clinical Spectrum of the Sick Sinus Syndrome". Circulation. 46 (1): 5–13. doi:10.1161/01.CIR.46.1.5. ISSN 0009-7322.
- ↑ Rodriguez RD, Schocken DD (1990). "Update on sick sinus syndrome, a cardiac disorder of aging". Geriatrics. 45 (1): 26–30, 33–6. PMID 2403955.