Macroglossia: Difference between revisions
Carlos Lopez (talk | contribs) No edit summary |
Carlos Lopez (talk | contribs) No edit summary |
||
(13 intermediate revisions by the same user not shown) | |||
Line 15: | Line 15: | ||
{{SI}} | {{SI}} | ||
{{CMG}} | {{CMG}} {{CLG}} | ||
==Overview== | ==Overview== | ||
The common causes of macroglossia include [[acromegaly]], [[amyloidosis]], [[beckwith-Wiedemann syndrome]], [[congenital hypothyroidism]] and [[down syndrome]]. | |||
==Causes== | ==Causes== | ||
===Life Threatening Causes=== | |||
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. | |||
===Common Causes=== | |||
*[[Acromegaly]] | *[[Acromegaly]] | ||
*[[Amyloidosis]] | *[[Amyloidosis]] | ||
*[[Beckwith-Wiedemann syndrome]] | *[[Beckwith-Wiedemann syndrome]] | ||
*[[Congenital hypothyroidism]] | *[[Congenital hypothyroidism]] | ||
*[[Down syndrome]] | |||
*[[Hurler syndrome]] | *[[Hurler syndrome]] | ||
*[[ | *[[I-cell disease]] | ||
===Causes by Organ System=== | ===Causes by Organ System=== | ||
Line 43: | Line 37: | ||
{|style="width:80%; height:100px" border="1" | {|style="width:80%; height:100px" border="1" | ||
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | ||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Cardiac | |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Cardiac amyloidosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
Line 51: | Line 45: | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Dermatologic''' | | '''Dermatologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Hemangioma]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Angioedema]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Ear Nose Throat''' | | '''Ear Nose Throat''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Acromegaly]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| [[Acromegaly]], [[congenital hypothyroidism]], [[growth hormone secreting pituitary adenoma]], [[ | |bgcolor="Beige"| [[Acromegaly]], [[congenital hypothyroidism]], [[growth hormone secreting pituitary adenoma]], [[hypothyroidism]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
Line 75: | Line 69: | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"|[[Alpha-mannosidosis]], [[Beckwith-Wiedemann syndrome]], chromosome 12p tetrasomy syndrome, chromosome 9q deletion syndrome, congenital micrognathia, [[down syndrome]], [[gM1 gangliosidoses]], gM3 gangliosidoses, [[glycogen storage disease]], [[Hunter syndrome]], [[Hurler syndrome]], [[Limb-girdle muscular dystrophy]], [[lymphoma]], [[monoclonal gammopathy of undetermined significance]], [[I-cell disease]], [[omphalocele]], [[Smith-Lemli-Opitz syndrome]], [[Pompe disease]], [[Potocki-Lupski syndrome]], [[Simpson-Golabi-Behmel syndrome]], [[tongue cancer]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
|bgcolor="Beige"|[[Multiple myeloma]] | |bgcolor="Beige"|[[Multiple myeloma]], [[monoclonal gammopathy of undetermined significance]], [[lymphoma]], [[down syndrome]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
Line 91: | Line 85: | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal / Ortho''' | | '''Musculoskeletal / Ortho''' | ||
|bgcolor="Beige"| [[Acromegaly]], [[Beckwith-Wiedemann syndrome]], [[congenital hypothyroidism]], [[cystic hygroma]], [[Limb-girdle muscular dystrophy]], [[multiple myeloma]] | |bgcolor="Beige"| [[Acromegaly]], [[Beckwith-Wiedemann syndrome]], [[congenital hypothyroidism]], [[cystic hygroma]], [[Limb-girdle muscular dystrophy]], [[multiple myeloma]], [[sleep apnea]], [[Simpson-Golabi-Behmel syndrome]], [[Beckwith-Wiedemann syndrome]], [[tongue cancer]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Neurologic''' | | '''Neurologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"|[[Neurofibromatosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
Line 107: | Line 101: | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Oncologic''' | | '''Oncologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Hemangioma]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Ophthalmologic''' | | '''Ophthalmologic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
Line 119: | Line 113: | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Psychiatric''' | | '''Psychiatric''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
Line 127: | Line 121: | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Renal / Electrolyte''' | | '''Renal / Electrolyte''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Rheum / Immune / Allergy''' | | '''Rheum / Immune / Allergy''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Angioedema]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
Line 147: | Line 141: | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Sleep apnea]] | ||
|- | |- | ||
|} | |} | ||
===Causes in Alphabetical Order=== | ===Causes in Alphabetical Order=== | ||
{{columns-list|2| | |||
* 17q21.31 duplication syndrome | |||
* 22q11.2 duplication syndrome | |||
* 5q35 microduplication syndrome | |||
* [[Acromegaly]] | |||
*[[Alpha-mannosidosis]] | |||
*[[Cardiac amyloidosis]] | |||
*[[Amyloidosis]] | |||
*[[Angioedema]] | |||
*[[Beckwith-Wiedemann syndrome]] | |||
* Chromosome 12p tetrasomy syndrome | |||
* Chromosome 9q deletion syndrome | |||
* [[Congenital hypothyroidism]] | |||
* Congenital micrognathia | |||
* [[Cystic hygroma]] | |||
* Dialysis-related amyloidosis | |||
* [[Down syndrome]] | |||
* [[Gangliosidosis GM1, type 1]] | |||
* Gangliosidosis GM3 | |||
* Gastrointestinal amyloidosis | |||
*[[Glycogen storage disease]] | |||
*[[Growth hormone secreting pituitary adenoma]] | |||
*[[Hemangioma]] | |||
*[[Hurler syndrome]] | |||
*[[Hypothyroidism]] | |||
*[[Congenital hypothyroidism]] | |||
*[[I-cell disease]] | |||
* Immunoglobulin light chain amyloidosis | |||
*[[Limb-girdle muscular dystrophy]] | |||
*[[Lymphangioma]] | |||
*[[Lymphoma]] | |||
*[[Monoclonal gammopathy of undetermined significance]] | |||
*[[Mucolipidosis II alpha/beta]] | |||
* Mucopolysaccharidosis VII | |||
*[[Multiple myeloma]] | |||
*[[Neurofibromatosis]] | |||
*[[Sleep apnea]] | |||
*[[Omphalocele]] | |||
*[[Opitz-Frias syndrome]] | |||
*[[Pompe disease]] | |||
*[[Potocki-Lupski syndrome]] | |||
* Schinzel-Giedion midface-retraction syndrome | |||
*[[Simpson-Golabi-Behmel syndrome]] | |||
*[[Tongue cancer]] | |||
}} | |||
Latest revision as of 16:12, 28 October 2015
Macroglossia | |
ICD-10 | Q38.2 |
---|---|
ICD-9 | 529.8 |
OMIM | 153630 |
DiseasesDB | 7689 |
MeSH | D008260 |
WikiDoc Resources for Macroglossia |
Articles |
---|
Most recent articles on Macroglossia Most cited articles on Macroglossia |
Media |
Powerpoint slides on Macroglossia |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Macroglossia at Clinical Trials.gov Clinical Trials on Macroglossia at Google
|
Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Macroglossia
|
Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Macroglossia Discussion groups on Macroglossia Patient Handouts on Macroglossia Directions to Hospitals Treating Macroglossia Risk calculators and risk factors for Macroglossia
|
Healthcare Provider Resources |
Causes & Risk Factors for Macroglossia |
Continuing Medical Education (CME) |
International |
|
Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Carlos A Lopez, M.D. [2]
Overview
The common causes of macroglossia include acromegaly, amyloidosis, beckwith-Wiedemann syndrome, congenital hypothyroidism and down syndrome.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
- Acromegaly
- Amyloidosis
- Beckwith-Wiedemann syndrome
- Congenital hypothyroidism
- Down syndrome
- Hurler syndrome
- I-cell disease
Causes by Organ System
Cardiovascular | Cardiac amyloidosis |
Chemical / poisoning | No underlying causes |
Dermatologic | Hemangioma |
Drug Side Effect | Angioedema |
Ear Nose Throat | Acromegaly |
Endocrine | Acromegaly, congenital hypothyroidism, growth hormone secreting pituitary adenoma, hypothyroidism |
Environmental | No underlying causes |
Gastroenterologic | No underlying causes |
Genetic | Alpha-mannosidosis, Beckwith-Wiedemann syndrome, chromosome 12p tetrasomy syndrome, chromosome 9q deletion syndrome, congenital micrognathia, down syndrome, gM1 gangliosidoses, gM3 gangliosidoses, glycogen storage disease, Hunter syndrome, Hurler syndrome, Limb-girdle muscular dystrophy, lymphoma, monoclonal gammopathy of undetermined significance, I-cell disease, omphalocele, Smith-Lemli-Opitz syndrome, Pompe disease, Potocki-Lupski syndrome, Simpson-Golabi-Behmel syndrome, tongue cancer |
Hematologic | Multiple myeloma, monoclonal gammopathy of undetermined significance, lymphoma, down syndrome |
Iatrogenic | No underlying causes |
Infectious Disease | No underlying causes |
Musculoskeletal / Ortho | Acromegaly, Beckwith-Wiedemann syndrome, congenital hypothyroidism, cystic hygroma, Limb-girdle muscular dystrophy, multiple myeloma, sleep apnea, Simpson-Golabi-Behmel syndrome, Beckwith-Wiedemann syndrome, tongue cancer |
Neurologic | Neurofibromatosis |
Nutritional / Metabolic | Cardiac amyloidosis, amyloidosis, gM1 gangliosidoses, gM3 gangliosidoses, Hunter syndrome, immunoglobulin light chain amyloidosis, I-cell disease, Pompe disease, Potocki-Lupski syndrome |
Obstetric/Gynecologic | No underlying causes |
Oncologic | Hemangioma |
Ophthalmologic | No underlying causes |
Overdose / Toxicity | No underlying causes |
Psychiatric | No underlying causes |
Pulmonary | No underlying causes |
Renal / Electrolyte | No underlying causes |
Rheum / Immune / Allergy | Angioedema |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | Sleep apnea |
Causes in Alphabetical Order
Template:Congenital malformations and deformations of digestive system