Middle East respiratory syndrome coronavirus infection diagnostic criteria: Difference between revisions
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===Suspected Case=== | ===Suspected Case=== | ||
For a patient to be categorized as a suspected case or patient under investigation (PUI) it should meet the following criteria, either A or B:<ref name=MMWR>{{cite web | title = Updated Information on the Epidemiology of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection and Guidance for the Public, Clinicians, and Public Health Authorities, 2012–2013 | url = http://www.cdc.gov/coronavirus/mers/case-def.html }}</ref><br> | For a patient to be categorized as a suspected case or patient under investigation (PUI) it should meet the following criteria, either A or B:<ref name=MMWR>{{cite web | title = Updated Information on the Epidemiology of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection and Guidance for the Public, Clinicians, and Public Health Authorities, 2012–2013 | url = http://www.cdc.gov/coronavirus/mers/case-def.html }}</ref><br> | ||
'''A.''' [[ Fever]] (≥38°C, 100.4°F) and [[pneumonia]] or [[acute respiratory distress syndrome]] (based on clinical or radiological evidence) | '''A.''' [[ Fever]] (≥38°C, 100.4°F) and [[pneumonia]] or [[acute respiratory distress syndrome]] (based on clinical or radiological evidence) | ||
: ''AND EITHER'' | : ''AND EITHER''<br> | ||
:: History of travel from countries in or near the Arabian Peninsula within 14 days before symptom onset<br> | |||
:: History of travel from countries in or near the Arabian Peninsula within 14 days before symptom onset | : ''OR''<br> | ||
:: Close contact with a symptomatic traveler who developed [[fever]] and acute [[respiratory illness]] (not necessarily [[pneumonia]]) within 14 days after traveling from countries in or near the Arabian Peninsula<br> | |||
: ''OR'' | : ''OR''<br> | ||
:: Member of a cluster of patients with severe acute [[respiratory illness]] (e.g.[[ fever]] and [[pneumonia]] requiring hospitalization) of unknown [[etiology]] in which [[MERS-CoV]] is being evaluated, in consultation with state and local health departments<br> | |||
:: Close contact with a symptomatic traveler who developed [[fever]] and acute [[respiratory illness]] (not necessarily [[pneumonia]]) within 14 days after traveling from countries in or near the Arabian Peninsula | |||
: ''OR'' | |||
:: Member of a cluster of patients with severe acute [[respiratory illness]] (e.g.[[ fever]] and [[pneumonia]] requiring hospitalization) of unknown [[etiology]] in which [[MERS-CoV]] is being evaluated, in consultation with state and local health departments | |||
''OR'' | ''OR'' | ||
'''B.''' [[Fever]] (≥38°C, 100.4°F) | '''B.''' [[Fever]] (≥38°C, 100.4°F)<br> | ||
: ''AND''<br> | |||
: ''AND'' | :: Symptoms of respiratory illness (not necessarily pneumonia; e.g., [[cough]], [[shortness of breath]]) <br> | ||
: ''AND''<br> | |||
:: Symptoms of respiratory illness (not necessarily pneumonia; e.g., [[cough]], [[shortness of breath]]) | |||
: ''AND'' | |||
:: Being in a healthcare facility (as a patient, worker, or visitor) within 14 days before symptom onset in a country or territory in or near the Arabian Peninsula in which recent healthcare-associated cases of MERS have been identified | :: Being in a healthcare facility (as a patient, worker, or visitor) within 14 days before symptom onset in a country or territory in or near the Arabian Peninsula in which recent healthcare-associated cases of MERS have been identified | ||
Revision as of 17:45, 23 June 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Healthcare providers should be prepared to detect persons at risk for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection; this requires clinical judgment as information on modes of transmission of MERS-CoV and clinical presentation of MERS is limited and continues to evolve. Patients can be categorized as suspected, probable and confirmed case of MERS-CoV infection.
Diagnostic Criteria for MERS-CoV Infection
Suspected Case
For a patient to be categorized as a suspected case or patient under investigation (PUI) it should meet the following criteria, either A or B:[1]
A. Fever (≥38°C, 100.4°F) and pneumonia or acute respiratory distress syndrome (based on clinical or radiological evidence)
- AND EITHER
- History of travel from countries in or near the Arabian Peninsula within 14 days before symptom onset
- History of travel from countries in or near the Arabian Peninsula within 14 days before symptom onset
- OR
- Close contact with a symptomatic traveler who developed fever and acute respiratory illness (not necessarily pneumonia) within 14 days after traveling from countries in or near the Arabian Peninsula
- Close contact with a symptomatic traveler who developed fever and acute respiratory illness (not necessarily pneumonia) within 14 days after traveling from countries in or near the Arabian Peninsula
- OR
- Member of a cluster of patients with severe acute respiratory illness (e.g.fever and pneumonia requiring hospitalization) of unknown etiology in which MERS-CoV is being evaluated, in consultation with state and local health departments
- Member of a cluster of patients with severe acute respiratory illness (e.g.fever and pneumonia requiring hospitalization) of unknown etiology in which MERS-CoV is being evaluated, in consultation with state and local health departments
OR
B. Fever (≥38°C, 100.4°F)
- AND
- Symptoms of respiratory illness (not necessarily pneumonia; e.g., cough, shortness of breath)
- Symptoms of respiratory illness (not necessarily pneumonia; e.g., cough, shortness of breath)
- AND
- Being in a healthcare facility (as a patient, worker, or visitor) within 14 days before symptom onset in a country or territory in or near the Arabian Peninsula in which recent healthcare-associated cases of MERS have been identified
Probable Case
According to the CDC, it is considered a probable case of MERS-CoV infection, an individual under investigation who has missing or inconclusive laboratory test results for the infection and that has been in close contact with another individual who is a "laboratory-confirmed case" of MERS-CoV infection.[1]
Confirmed Case
According to the CDC, a confirmed case of MERS-CoV infection is considered an individual who shows laboratory confirmation of infection by MERS-CoV.[1]