Colon polyps natural history, complications and prognosis: Difference between revisions

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*Common complications of colon polyps include:<ref name="Bonnington2016">{{cite journal|last1=Bonnington|first1=Stewart N|title=Surveillance of colonic polyps: Are we getting it right?|journal=World Journal of Gastroenterology|volume=22|issue=6|year=2016|pages=1925|issn=1007-9327|doi=10.3748/wjg.v22.i6.1925}}</ref><ref name="ShussmanWexner2014">{{cite journal|last1=Shussman|first1=N.|last2=Wexner|first2=S. D.|title=Colorectal polyps and polyposis syndromes|journal=Gastroenterology Report|volume=2|issue=1|year=2014|pages=1–15|issn=2052-0034|doi=10.1093/gastro/got041}}</ref>
*Common complications of colon polyps include:<ref name="Bonnington2016">{{cite journal|last1=Bonnington|first1=Stewart N|title=Surveillance of colonic polyps: Are we getting it right?|journal=World Journal of Gastroenterology|volume=22|issue=6|year=2016|pages=1925|issn=1007-9327|doi=10.3748/wjg.v22.i6.1925}}</ref><ref name="ShussmanWexner2014">{{cite journal|last1=Shussman|first1=N.|last2=Wexner|first2=S. D.|title=Colorectal polyps and polyposis syndromes|journal=Gastroenterology Report|volume=2|issue=1|year=2014|pages=1–15|issn=2052-0034|doi=10.1093/gastro/got041}}</ref>
**[[Colorectal cancer]]
**[[Colorectal cancer]]
**[[Gastrointestinal bleeding]]
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**[[Bleeding]] following [[polypectomy]]
:*[[Gastrointestinal bleeding]]
:*[[Bleeding]] following [[polypectomy]]


===Prognosis===
===Prognosis===

Revision as of 21:15, 26 January 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]

Overview

Colon polyps are very common in general population. They are usually found during screening colonoscopy. Polyps might grow gradually and cause symptoms including obstruction, bleeding, and changes in bowel habits. Some of them might progress to colorectal cancer. Therefore, it is advisable to resect all polyps that are found during colonoscopy and send the tissue biopsy for pathology. Prognosis of colon polyps is generally excellent. The presence of multiple polyps is associated with genetic disorders with a particularly poor prognosis.

Natural History, Complications, and Prognosis

Natural History

  • Colon polyps are very common in general population.[1]
  • They are usually found during screening colonoscopy.[2]
  • Polyps might grow gradually and cause symptoms including obstruction, bleeding, and changes in bowel habits.
  • Some of them might have malignant potential.
  • If left untreated, it may progress to develop colorectal cancer. The progression from an adenomatous polyp to colorectal cancer may take 10-15 years. 
  • All polyps are recommended to be resected.

Complications

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Prognosis

  • Prognosis of colon polyps is generally excellent.[1]
  • The presence of multiple polyps is associated with genetic disorders with a particularly poor prognosis.
  • Colon polyps that are associated with BRAF and KRAS mutations have a poor prognosis.[4]

References

  1. 1.0 1.1 Huang, Christopher S; Farraye, Francis A; Yang, Shi; O'Brien, Michael J (2010). "The Clinical Significance of Serrated Polyps". The American Journal of Gastroenterology. 106 (2): 229–240. doi:10.1038/ajg.2010.429. ISSN 0002-9270.
  2. 2.0 2.1 Bonnington, Stewart N (2016). "Surveillance of colonic polyps: Are we getting it right?". World Journal of Gastroenterology. 22 (6): 1925. doi:10.3748/wjg.v22.i6.1925. ISSN 1007-9327.
  3. Shussman, N.; Wexner, S. D. (2014). "Colorectal polyps and polyposis syndromes". Gastroenterology Report. 2 (1): 1–15. doi:10.1093/gastro/got041. ISSN 2052-0034.
  4. Bettington, Mark; Walker, Neal; Clouston, Andrew; Brown, Ian; Leggett, Barbara; Whitehall, Vicki (2013). "The serrated pathway to colorectal carcinoma: current concepts and challenges". Histopathology. 62 (3): 367–386. doi:10.1111/his.12055. ISSN 0309-0167.

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