Traveller vaccination rotavirus: Difference between revisions

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==Disease cause==
==Disease cause==
Strains of highly contagious rotaviruses.
Strains of highly contagious [[Rotavirus|rotaviruses]].


==Transmission==
==Transmission==
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==Nature of the disease==
==Nature of the disease==
Rotavirus infection is characterized by watery diarrhoea, vomiting and fever mainly in children aged >2 years. Severe cases may require rapid rehydration therapy, especially in young infants.
Rotavirus infection is characterized by watery [[diarrhea]], [[vomiting]] and [[fever]] mainly in children aged >2 years. Severe cases may require rapid [[rehydration]] therapy, especially in young infants.


==Geographical distribution==
==Geographical distribution==
Worldwide it is a leading cause of dehydrating diarrhoea, but fatal outcomes occur predominantly in low-income countries.
Worldwide it is a leading cause of dehydrating [[diarrhea]], but fatal outcomes occur predominantly in low-income countries.


==Risk for travellers==
==Risk for travellers==
Unvaccinated children < 2 years of age are likely to be at increased risk of rotavirus infection in environments of poor hygiene. The risk for older children and adults, most of whom are immune, is negligible.
Unvaccinated children < 2 years of age are likely to be at increased risk of [[rotavirus]] infection in environments of poor hygiene. The risk for older children and adults, most of whom are [[immune]], is negligible.


==Vaccine==
==Vaccine==
Two live attenuated oral vaccines are available; one based on a single rotavirus strain (monovalent), the other on five rotavirus strains (pentavalent). When administered according to the respective national recommendations (or following the schedule of routine vaccination against DTP), these vaccines are efficacious and safe.
Two live attenuated oral vaccines are available; one based on a single rotavirus strain (monovalent), the other on five rotavirus strains (pentavalent). When administered according to the respective national recommendations (or following the schedule of routine vaccination against DTP), these vaccines are efficacious and safe.

Latest revision as of 16:04, 21 April 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]

Overview

Protection against rotavirus diarrhoea is not specific to the needs of travelling children. In countries where vaccination of infants against rotavirus infections is routinely administered, incomplete or missed vaccination according to age of the child and national recommendations should be offered.

Disease cause

Strains of highly contagious rotaviruses.

Transmission

Mainly by the faecal-oral route, and by direct or indirect contact.

Nature of the disease

Rotavirus infection is characterized by watery diarrhea, vomiting and fever mainly in children aged >2 years. Severe cases may require rapid rehydration therapy, especially in young infants.

Geographical distribution

Worldwide it is a leading cause of dehydrating diarrhea, but fatal outcomes occur predominantly in low-income countries.

Risk for travellers

Unvaccinated children < 2 years of age are likely to be at increased risk of rotavirus infection in environments of poor hygiene. The risk for older children and adults, most of whom are immune, is negligible.

Vaccine

Two live attenuated oral vaccines are available; one based on a single rotavirus strain (monovalent), the other on five rotavirus strains (pentavalent). When administered according to the respective national recommendations (or following the schedule of routine vaccination against DTP), these vaccines are efficacious and safe.