Transient global amneisa epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hasnain Ali Moryani, MBBS.
Overview
- Each year, approximately 3 to 8 persons per 100,000 population experience an episode of transient global amnesia[1].
- The condition occurs more frequently in persons older than 50 years of age[1].
Epidemiology of Transient Global Amnesia
- In a retrospective series of 277 cases, the mean age was 62 years[2].
- Sex distribution has varied across studies:
- In most series, about 15% of patients have had more than one episode[2].
- Among those with recurrent episodes, the average interval between episodes was approximately 2 years, and almost two thirds had three or more definite or probable episodes[2].
- Estimates of recurrence frequency and intervals vary among studies[2][4].
- Data from a retrospective series of 1044 patients suggested that younger age at first episode and a personal or family history of migraine were associated with future episodes, although these findings have not been consistently affirmed[4].
- Cardiovascular risk factors have been overrepresented in some series but are considered commensurate with the typical age range of affected patients[5].
- A higher risk of transient global amnesia has been reported among patients with migraine compared with those without migraine[6].
- Rare reports of transient global amnesia in adolescents have been linked to athletic activity and a history of migraine[7].
References
- ↑ 1.0 1.1 Ropper AH (February 2023). "Transient Global Amnesia". N Engl J Med. 388 (7): 635–640. doi:10.1056/NEJMra2213867. PMID 36791163 Check
|pmid=value (help). - ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Miller JW, Petersen RC, Metter EJ, Millikan CH, Yanagihara T (May 1987). "Transient global amnesia: clinical characteristics and prognosis". Neurology. 37 (5): 733–7. doi:10.1212/wnl.37.5.733. PMID 3574671.
- ↑ 3.0 3.1 Rollinson RD (October 1978). "Transient global amnesia--a review of 213 cases from the literature". Aust N Z J Med. 8 (5): 547–9. doi:10.1111/j.1445-5994.1978.tb02598.x. PMID 369512.
- ↑ 4.0 4.1 Morris KA, Rabinstein AA, Young NP (December 2020). "Factors Associated With Risk of Recurrent Transient Global Amnesia". JAMA Neurol. 77 (12): 1551–1558. doi:10.1001/jamaneurol.2020.2943. PMC 7489420 Check
|pmc=value (help). PMID 32865551 Check|pmid=value (help). - ↑ Zorzon M, Antonutti L, Masè G, Biasutti E, Vitrani B, Cazzato G (September 1995). "Transient global amnesia and transient ischemic attack. Natural history, vascular risk factors, and associated conditions". Stroke. 26 (9): 1536–42. doi:10.1161/01.str.26.9.1536. PMID 7660394.
- ↑ Liampas I, Siouras AS, Siokas V, Tsouris Z, Rikos D, Brotis A, Aloizou AM, Dastamani M, Dardiotis E (January 2022). "Migraine in transient global amnesia: a meta-analysis of observational studies". J Neurol. 269 (1): 184–196. doi:10.1007/s00415-020-10363-y. PMID 33388926 Check
|pmid=value (help). - ↑ Tosi L, Righetti CA (February 1997). "Transient global amnesia and migraine in young people". Clin Neurol Neurosurg. 99 (1): 63–5. doi:10.1016/s0303-8467(96)00595-1. PMID 9107472.