Transient global amneisa diagnostic criteria
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Overview of Diagnostic Criteria of Transient Global Amnesia
Transient global amnesia is a sudden, temporary disturbance of memory in which the patient cannot retain new information and has a period of retrograde amnesia, while remaining alert, oriented to person, and otherwise neurologically normal. Diagnostic criteria focus on a witnessed, isolated episode of amnesia that resolves within 24 hours, without seizures, head trauma, or other major neurologic deficits.[1][2][3]
Diagnostic Criteria
- Attack is witnessed
- Clear anterograde amnesia
- Disturbance limited to memory
- Dysfunction is confined to repetitive queries and amnesia[2][3].
- No clouding of consciousness[2][3].
- No general cognitive defect aside from memory disturbance on bedside testing[1].
- No loss of personal identity (the patient knows who they are and recognizes familiar people, except for events within the retrograde gap)[2][3].
- No other major neurologic signs
- No seizure or recent head trauma
- Transient course
Table
| Source | Diagnostic Features |
| Adapted from Caplan[5] | Attack is witnessed |
| Dysfunction limited to repetitive queries and amnesia | |
| No other major neurologic signs or symptoms | |
| Memory loss is transient, usually lasting hours to a day | |
| Adapted from Hodges & Warlow[6] | Attack is witnessed |
| Clear anterograde amnesia | |
| No clouding of consciousness, cognitive defect, or loss of personal identity | |
| Attack resolves within 24 hours | |
| No focal neurologic signs during or after the attack | |
| No epileptic features | |
| No recent head injury or active epilepsy |
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 BENDER MB (March 1960). "Single episode of confusion with amnesia". Bull N Y Acad Med. 36 (3): 197–207. PMC 1806291. PMID 13798787.
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 Mangla A, Navi BB, Layton K, Kamel H (February 2014). "Transient global amnesia and the risk of ischemic stroke". Stroke. 45 (2): 389–93. doi:10.1161/STROKEAHA.113.003916. PMC 3946840. PMID 24309586.
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 Lee SH, Kim KY, Lee JW, Park SJ, Jung JM (April 2022). "Risk of ischaemic stroke in patients with transient global amnesia: a propensity-matched cohort study". Stroke Vasc Neurol. 7 (2): 101–107. doi:10.1136/svn-2021-001006. PMC 9067272 Check
|pmc=value (help). PMID 34702748 Check|pmid=value (help). - ↑ Baker J, Savage S, Milton F, Butler C, Kapur N, Hodges J, Zeman A (2021). "The syndrome of transient epileptic amnesia: a combined series of 115 cases and literature review". Brain Commun. 3 (2): fcab038. doi:10.1093/braincomms/fcab038. PMC 8047097 Check
|pmc=value (help). PMID 33884371 Check|pmid=value (help). - ↑ Caplan LR (October 2022). "Transient global amnesia. What's in a name?". J Neurol Sci. 441: 120348. doi:10.1016/j.jns.2022.120348. PMID 35940029 Check
|pmid=value (help). - ↑ Hodges JR, Warlow CP (October 1990). "Syndromes of transient amnesia: towards a classification. A study of 153 cases". J Neurol Neurosurg Psychiatry. 53 (10): 834–43. doi:10.1136/jnnp.53.10.834. PMC 488242. PMID 2266362.