Sulfafurazole

Sulfafurazole

Clinical data
AHFS/Drugs.com	International Drug Names
MedlinePlus	a601049
Pregnancy category	To be avoided within two months of term
Routes of administration	Oral
ATC code	J01EB05 (WHO) S01AB02 (WHO) Template:ATCvet
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Excretion	Excreted unchanged in urine
Identifiers
IUPAC name 4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
CAS Number	127-69-5 Y
PubChem CID	5344
DrugBank	DB00263 N
UNII	740T4C525W
KEGG	D00450 Y
ChEMBL	ChEMBL453 N
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C11H13N3O3S
Molar mass	267.30 g/mol
3D model (JSmol)	Interactive image
SMILES CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of Gram-negative and Gram-positive organisms. It is sometimes given in combination with erythromycin (see erythromycin/Sulfafurazole) or phenazopyridine. It is used locally in a 4% solution or ointment.

Synthesis

See also

• Sulfamethoxazole
• Sulfapyridine