Oxetacaine

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Oxetacaine
Oxetacaine.png
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral, topical
ATC code
Pharmacokinetic data
Elimination half-life1 hour
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
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Chemical and physical data
FormulaC28H41N3O3
Molar mass467.643 g/mol
3D model (JSmol)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Oxetacaine (INN, also known as oxethazaine) is a potent local anesthetic. It is administered orally (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis. It is also used topically in the management of hemorrhoid pain. Oral oxetacaine preparations are available in several countries, including India, South Africa, Japan and Brazil, but not the United States.

Unlike most local anesthetics, oxetacaine is active even in strongly acidic conditions.[1]

References

  1. Seifter J, Glassman JM, Hudyma GM (1962). "Oxethazaine and related congeners: a series of highly potent local anesthetics". Proc Soc Exp Biol Med. 109: 664–8. doi:10.3181/00379727-109-27300. PMID 13910333.

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