Nucleoporin 54

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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Nucleoporin 54 (Nup54) is a protein that in humans is encoded by the NUP54 gene.[1][2]

Function

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset.[2]

References

  1. Hu T, Guan T, Gerace L (Sep 1996). "Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins". J Cell Biol. 134 (3): 589–601. doi:10.1083/jcb.134.3.589. PMC 2120945. PMID 8707840.
  2. 2.0 2.1 "Entrez Gene: NUP54 nucleoporin 54kDa".

Further reading