Lanatoside C

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Lanatoside C
Isolanid.png
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC49H76O20
Molar mass985.116 g/mol

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Lanatoside C (or isolanid) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Lanatoside C can be used orally[1] or by the intravenous route.[2] It is marketed in a number of countries and is also available in generic form.[3] Its main indications are rapid response atrial fibrillation and paroxysmal supraventricular tachycardia,[citation needed] two common types of arrhythmia.

It is found in Digitalis lanata.[4]

Chemistry

The substance is composed of four monosaccharides (glucose, 3-acetyldigitoxose and two digitoxoses) and an aglycon named digoxigenin.[5]

References

  1. PMID 506267 (PMID 506267)
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  2. PMID 5600177 (PMID 5600177)
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  3. "Lanatoside C". International Drug Names. Drugs.com.
  4. Determination of Lanatoside C and Digoxin in Digitalis lanata by Hplc and Its Application to Analysis of the Fermented Leaf Powder. Yukari Ikeda, Youichi Fujii and Mitsuru Yamazaki, J. Nat. Prod., 1992, volume 55, issue 6, pages 748–752, doi:10.1021/np50084a007
  5. Desai, U. R. (2005). "Cardiac Glycosides". VCU School of Pharmacy.

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