Idiopathic interstitial pneumonia differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Overview
Careful and extensive investigations in multiple visits to ensure the idiopathic interstitial pneumonia is accurately diagnosed. :*10 to 20% of patients with IPF have positive rheumatoid factor or positive circulating anti-nuclear antibodies (ANAs), but rarely are titers high. However only the presence of high titers (> 1:160) would suggest the presence of a connective tissue disease . [1] [2] [3]*
Differential Diagnosis
- Sarcoidosis
- Hypersensitivity pneumonitis
- Collagen vascular disease
- Human immunodeficiency virus, NSIP is commonly occuring in patients who have AIDS.[4][5][6][7][8]
- Antiphospholipid antibody syndrome
- Chronic obstructive pulmonary disease
- Coalworker's pneumoconiosis
- Drug induced pulmonary toxicity
- Lymphocytic interstitial pneumonia
- Idiopathic pulmonary fibrosis
- Diaphragmatic paralysis
- Primary pulmonary hypertension
- Restrictive lung disease
- Silicosis
References
- ↑ Scadding, JG.; Hinson, KF. (1967). "Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lungs). Correlation of histology at biopsy with prognosis". Thorax. 22 (4): 291–304. PMID 6035793. Unknown parameter
|month=ignored (help) - ↑ Nagaya, H.; Buckley, CE.; Sieker, HO. (1969). "Positive antinuclear factor in patients with unexplained pulmonary fibrosis". Ann Intern Med. 70 (6): 1135–45. PMID 4892605. Unknown parameter
|month=ignored (help) - ↑ Nagaya, H.; Sieker, HO. (1972). "Pathogenetic mechanisms of interstitial pulmonary fibrosis in patients with serum antinuclear factor. A histologic and clinical correlation". Am J Med. 52 (1): 51–62. PMID 4536709. Unknown parameter
|month=ignored (help) - ↑ Suffredini, AF.; Ognibene, FP.; Lack, EE.; Simmons, JT.; Brenner, M.; Gill, VJ.; Lane, HC.; Fauci, AS.; Parrillo, JE. (1987). "Nonspecific interstitial pneumonitis: a common cause of pulmonary disease in the acquired immunodeficiency syndrome". Ann Intern Med. 107 (1): 7–13. PMID 3496030. Unknown parameter
|month=ignored (help) - ↑ Simmons, JT.; Suffredini, AF.; Lack, EE.; Brenner, M.; Ognibene, FP.; Shelhamer, JH.; Lane, HC.; Fauci, AS.; Masur, H. (1987). "Nonspecific interstitial pneumonitis in patients with AIDS: radiologic features". AJR Am J Roentgenol. 149 (2): 265–8. doi:10.2214/ajr.149.2.265. PMID 3496748. Unknown parameter
|month=ignored (help) - ↑ Sattler, F.; Nichols, L.; Hirano, L.; Hiti, A.; Hofman, F.; Hughlett, C.; Zeng, L.; Boylen, CT.; Koss, M. (1997). "Nonspecific interstitial pneumonitis mimicking Pneumocystis carinii pneumonia". Am J Respir Crit Care Med. 156 (3 Pt 1): 912–7. doi:10.1164/ajrccm.156.3.9612050. PMID 9310013. Unknown parameter
|month=ignored (help) - ↑ Travis, WD.; Fox, CH.; Devaney, KO.; Weiss, LM.; O'Leary, TJ.; Ognibene, FP.; Suffredini, AF.; Rosen, MJ.; Cohen, MB. (1992). "Lymphoid pneumonitis in 50 adult patients infected with the human immunodeficiency virus: lymphocytic interstitial pneumonitis versus nonspecific interstitial pneumonitis". Hum Pathol. 23 (5): 529–41. PMID 1314778. Unknown parameter
|month=ignored (help) - ↑ Griffiths, MH.; Miller, RF.; Semple, SJ. (1995). "Interstitial pneumonitis in patients infected with the human immunodeficiency virus". Thorax. 50 (11): 1141–6. PMID 8553268. Unknown parameter
|month=ignored (help)