Hereditary pancreatitis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]
Overview
The incidence of hereditary pancreatitis is approximately 3.5–10 per 100,000 individuals in Europe and the USA. In Western countries, the prevalence was found to be 0.3/100 000. Hereditary pancreatitis commonly affects younger age group. The median age at which first diagnosis is made is 19 years. The median age at which the symptoms develop is 10 years.
Epidemiology and Demographics
Incidence
- The incidence of hereditary pancreatitis is approximately 3.5–10 per 100,000 individuals in Europe and the USA.[1][2]
Prevalence
- In Western countries, the prevalence was found to be 0.3/100 000.
Age
- Hereditary pancreatitis commonly affects younger age group.
- The median age at which first diagnosis is made is 19 years.[3][4]
- The median age at which the symptoms develop is 10 years.[3][4]
- In some patients, the disease may develop before 5 years of age.[5][6]
Race
- There is no racial predilection to Hereditary pancreatitis.
Gender
- Hereditary pancreatitis affects men and women equally.
References
- ↑ Andersen BN, Pedersen NT, Scheel J, Worning H (1982). "Incidence of alcoholic chronic pancreatitis in Copenhagen". Scand. J. Gastroenterol. 17 (2): 247–52. PMID 7134849.
- ↑ Barkin JS, Fayne SD (1986). "Chronic pancreatitis: update 1986". Mt. Sinai J. Med. 53 (5): 404–8. PMID 3489182.
- ↑ 3.0 3.1 Howes N, Lerch MM, Greenhalf W, Stocken DD, Ellis I, Simon P, Truninger K, Ammann R, Cavallini G, Charnley RM, Uomo G, Delhaye M, Spicak J, Drumm B, Jansen J, Mountford R, Whitcomb DC, Neoptolemos JP (2004). "Clinical and genetic characteristics of hereditary pancreatitis in Europe". Clin. Gastroenterol. Hepatol. 2 (3): 252–61. PMID 15017610.
- ↑ 4.0 4.1 Rebours V, Boutron-Ruault MC, Schnee M, Férec C, Le Maréchal C, Hentic O, Maire F, Hammel P, Ruszniewski P, Lévy P (2009). "The natural history of hereditary pancreatitis: a national series". Gut. 58 (1): 97–103. doi:10.1136/gut.2008.149179. PMID 18755888.
- ↑ Sossenheimer MJ, Aston CE, Preston RA, Gates LK, Ulrich CD, Martin SP, Zhang Y, Gorry MC, Ehrlich GD, Whitcomb DC (1997). "Clinical characteristics of hereditary pancreatitis in a large family, based on high-risk haplotype. The Midwest Multicenter Pancreatic Study Group (MMPSG)". Am. J. Gastroenterol. 92 (7): 1113–6. PMID 9219780.
- ↑ Keim V, Bauer N, Teich N, Simon P, Lerch MM, Mössner J (2001). "Clinical characterization of patients with hereditary pancreatitis and mutations in the cationic trypsinogen gene". Am. J. Med. 111 (8): 622–6. PMID 11755505.