Goiter other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

Overview

Thyroid radioisotope scan may be helpful in the diagnosis of goiter. It is helpful in determining the functional status of the thyroid gland by distinguishing between nodules as hot, warm, or cold, based on the relative amount of uptake of radioactive isotope. The radioactive isotopes that are most commonly used include Iodine-123, Technetium-99m and Iodine -131.

Other Imaging Findings

Thyroid radioisotope scan may be helpful in the diagnosis of goiter. Findings on a thyroid radioisotope scan are:[1][2]

  • Helpful in determining the functional activity by distinguishing a nodule as hot, warm, or cold, based on the relative amount of uptake of radioactive isotope.
    • Hot nodules take up excessive amounts of isotope and indicate autonomously functioning nodules.
    • Cold nodules have no or reduced uptake of radioactive isotope and therefore indicate non-functional or hypofunctional thyroid tissue respectively.
    • Warm nodules appear grey and suggest normal thyroid function.
  • The radioactive isotopes most commonly include Iodine-123, Technetium-99m and Iodine-131.

References

  1. Hegedüs L, Bonnema SJ, Bennedbaek FN (2003). "Management of simple nodular goiter: current status and future perspectives". Endocr Rev. 24 (1): 102–32. doi:10.1210/er.2002-0016. PMID 12588812.
  2. Bahn RS, Castro MR (2011). "Approach to the patient with nontoxic multinodular goiter". J Clin Endocrinol Metab. 96 (5): 1202–12. doi:10.1210/jc.2010-2583. PMID 21543434.

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