Desquamative interstitial pneumonia

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and Keywords: Desquamative interstitial pneumonitis

Overview

Desquamative interstitial pneumonia is a form of idiopathic interstitial pneumonia featuring elevated levels of macrophages.

Historical Perspective

Its name is derived from the former belief that these macrophages were pneumocytes that had desquamated.[1]

Causes

It is associated with patients with a history of smoking.[2]

Treatment

Medical Therapy

Treatment with methylprednisolone has been reported.[3]

References

  1. Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease. St. Louis, Mo: Elsevier Saunders. p. 740. ISBN 0-7216-0187-1.
  2. Heyneman LE, Ward S, Lynch DA, Remy-Jardin M, Johkoh T, Müller NL (1999). "Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process?". AJR Am J Roentgenol. 173 (6): 1617–22. PMID 10584810. Unknown parameter |month= ignored (help)
  3. Paul K, Klettke U, Moldenhauer J; et al. (1999). "Increasing dose of methylprednisolone pulse therapy treats desquamative interstitial pneumonia in a child". Eur. Respir. J. 14 (6): 1429–32. PMID 10624777. Unknown parameter |month= ignored (help)





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