Congenital syphilis other diagnostic studies
Jump to navigation
Jump to search
|
Congenital syphilis Microchapters |
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Congenital syphilis other diagnostic studies On the Web |
|
American Roentgen Ray Society Images of Congenital syphilis other diagnostic studies |
|
Risk calculators and risk factors for Congenital syphilis other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]Aravind Kuchkuntla, M.B.B.S[3]
Overview
Pathologic examination of the placenta or umbilical cord by using specific fluorescent antitreponemal antibody staining and CSF analysis can be done.
Other Diagnostic Findings
CSF Analysis
Indications : Lumbar puncture is indicated in the following situations.[1]
- If the infant or child has signs and symptoms of congenital Syphilis.
- If there is no documentation of treatment for maternal infection during the period of gestation.
- If the mother was treated within 4 weeks of delivery.
- If the mother was inadequately treated or documentation of the treatment is incomplete.
- A four-fold decline in titer following therapy in the mother is not documented.
CSF Findings:
- Reactive CSF VDRL. [2]
- CSF pleocytosis(>25 white blood cells [WBC]/microL for infants <1 month)
- Elevated CSF protein (>150 mg/dL in term infants <1 month of age and >170 mg/dL in preterm infants <1 month of age)
References
- ↑ Phiske, MeghanaMadhukar (2014). "Current trends in congenital syphilis". Indian Journal of Sexually Transmitted Diseases and AIDS. 35 (1): 12. doi:10.4103/0253-7184.132404. ISSN 0253-7184.
- ↑ Workowski KA, Bolan GA, Centers for Disease Control and Prevention (2015). "Sexually transmitted diseases treatment guidelines, 2015". MMWR Recomm Rep. 64 (RR-03): 1–137. PMID 26042815.