Congenital syphilis historical perspective
|
Congenital syphilis Microchapters |
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Congenital syphilis historical perspective On the Web |
|
American Roentgen Ray Society Images of Congenital syphilis historical perspective |
|
Risk calculators and risk factors for Congenital syphilis historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2] Aravind Kuchkuntla, M.B.B.S[3]
Overview
Congenital syphilis was first described in an English 17th century in a pediatric textbook. Transplacental transmission from an asymptomatic infected mother was first described in 1906. Sir Jonathan Hutchinson described the triad of notched incisors, interstitial keratitis, and eighth cranial nerve deafness as a criterion for diagnosis of congenital syphilis.
Historical Perspective
- Sir Jonathan Hutchinson described the triad of notched incisors, interstitial keratitis, and eighth cranial nerve deafness as a criterion for diagnosis of congenital syphilis. The condition was well described in the 15th century and has long been recognized as a syndrome transmitted from an infected adult.
- In the 19th century congenital syphilis was believed to be transmitted during conception by the father’s sperm or during delivery in the birth canal, or from infected milk or breasts.[1]
- In 1905, Schaudinn and Hoffmann identified Spirochaeta pallida.
- Transplacental transmission from an asymptomatic infected mother was first described in 1906.[2]
- In 1943, Lentz and Ingraham reported penicillin as treatment for congenital syphilis.
- In 2006, the WHO launched a global effort to eliminate congenital syphilis.
References
- ↑ Obladen, Michael (2013). "Curse on Two Generations: A History of Congenital Syphilis". Neonatology. 103 (4): 274–280. doi:10.1159/000347107. ISSN 1661-7819.
- ↑ "Guidelines for the Prevention and Control of Congenital Syphilis".