Co-amilofruse

Co-amilofruse

Combination of
Amiloride	Potassium-sparing diuretic
Frusemide	Loop diuretic
[[{{{component3}}}]]	? Class
[[{{{component4}}}]]	? Class
[[{{{component5}}}]]	? Class
[[{{{component6}}}]]	? Class
Gene therapy
Clinical data
Routes of administration	Oral
ATC code	C03EB01 (WHO)
Physiological data
Legal status
Legal status	UK: POM (Prescription only)
Pharmacokinetic data
Identifiers
Chemical and physical data

Co-amilofruse (BAN) is a non-proprietary name used to denote a combination of amiloride and the formerly named frusemide (now the INN termed furosemide). Co-amilofruse in the treatment of fluid retension (oedema), either in the legs (peripheral edema) or on the lungs (pulmonary oedema). The stronger furosemide loop diuretic has a tendency to cause low potassium levels (hypokalaemia) that may be prevented by the potassium-sparing effects of amiloride.

Formulation

Two strengths of co-amilofruse are available:

• 2.5 mg amiloride with 20 mg furosemide, BAN of Co-amilofruse 2.5/20 (brand name Frumil LS)
• 5 mg amiloride with 40 mg furosemide, BAN of Co-amilofruse 5/4-0 (brand name Frumil)

References

• British National Formulary 2004