Cavernous sinus thrombosis diagnostic study of choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Magnetic resonance imaging (MRI) with MR venography is the gold standard test for the diagnosis of cavernous sinus thrombosis. The following findings on performing MRI are confirmatory for cavernous sinus thrombosis: Absent flow void in T1 and T2 and signal characteristics vary depending on the age of the thrombus but will be abnormal. Contrast-enhancement or lack of is not a reliable indicator as organising thrombus can enhance. Diagnosis can generally be made on venography.

Diagnostic Study of Choice

Study of choice

Magnetic resonance imaging (MRI) with MR venography is the gold standard test for the diagnosis of cavernous sinus thrombosis.[1][2][3]

Diagnostic results

The following findings on performing MRI are confirmatory for cavernous sinus thrombosis:

  • T1 and T2
    • Absent flow void
    • Signal characteristics vary depending on the age of the thrombus but will be abnormal.
  • Contrast-enhancement or lack of is not a reliable indicator as organising thrombus can enhance.
  • Diagnosis can generally be made on venography.

References

  1. Chiewvit P, Piyapittayanan S, Poungvarin N (2011). "Cerebral venous thrombosis: diagnosis dilemma". Neurol Int. 3 (3): e13. doi:10.4081/ni.2011.e13. PMC 3286153. PMID 22368772.
  2. Igarashi H, Igarashi S, Fujio N, Fukui K, Yoshida A (1995). "Magnetic resonance imaging in the early diagnosis of cavernous sinus thrombosis". Ophthalmologica. 209 (5): 292–6. doi:10.1159/000310635. PMID 8570157.
  3. Berge J, Louail C, Caillé JM (1994). "Cavernous sinus thrombosis diagnostic approach". J Neuroradiol. 21 (2): 101–17. PMID 8014656.

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