Budd-Chiari syndrome risk factors

Budd-Chiari syndrome Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Budd-Chiari syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Budd-Chiari syndrome risk factors On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Budd-Chiari syndrome risk factors All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Budd-Chiari syndrome risk factors
CDC on Budd-Chiari syndrome risk factors
Budd-Chiari syndrome risk factors in the news
Blogs on Budd-Chiari syndrome risk factors
Directions to Hospitals Treating Type page name here
Risk calculators and risk factors for Budd-Chiari syndrome risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]

Overivew

Approximately 80 percent of patients with the Budd-Chiari syndrome have an underlying disorder. Many patients may have more than one risk factor. Same patients may have multiple causes that predispose to the development of Budd-Chiari Syndrome. Associated risk factors include hematologic disorders, coagulopathies, chronic infections, chronic inflammatory diseases, tumors, congenital membranous obstructions.

Risk Factors

• Approximately 80 percent of patients with the Budd-Chiari syndrome have an underlying disorder. Many patients may have more than one risk factor. Same patient may have multiple causes that predispose to the development of Budd-Chiari Syndrome.
• Associated risk factors include:
• Hematologic disorders including:
  • Polycythemia rubra vera
  • Paroxysmal nocturnal hemoglobinuria
  • myeloproliferative disorder
  • Antiphospholipid antibody syndrome
  • Essential thrombocytosis
  • Inherited thrombotic diathesis

• Coagulopathies include the following:
  • Protein C deficiency
  • Protein S deficiency
  • Antithrombin III deficiency
  • Factor V Leiden deficiency
• Chronic infections like:
  • Hydatid cysts
  • Aspergillosis
  • Amebic abscess
  • Syphilis
  • Tuberculosis
• Chronic inflammatory diseases such as:
  • Behçet disease
  • Inflammatory bowel disease
  • Sarcoidosis
  • Systemic lupus erythematosus
  • Sjögren syndrome
  • Mixed connective-tissue disease
• Tumors such as
  • Hepatocellular carcinoma (HCC)
  • Renal cell carcinoma
  • Leiomyosarcoma
  • Adrenal carcinoma
  • Wilms tumor
  • Right atrial myxoma
• Congenital membranous obstructions that include the following:
  • Type I: Thin membrane is present in the vena cava or the atrium
  • Type II: A part of the vena cava is absent
  • Type III: The inferior vena cava (IVC) cannot be filled, and collaterals have developed
• Miscellaneous risk factors of Budd-Chiari syndrome include the following:
  • Alpha1-antitrypsin deficiency
  • Dacarbazine
  • Urethane
  • Hypoplasia of the suprahepatic veins
  • Postsurgical obstruction
  • Posttraumatic obstruction
  • Total parenteral nutrition (TPN): Budd-Chiari syndrome can be a complication of total parenteral nutrition (TPN) via an inferior vena cava (IVC) catheter in a neonate