Beriberi MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]

Overview

In Wernicke-Korsakoff Syndrome patients, MRI may show some changes, including atrophy of mamillary bodies and hyperintense signals in the mesial dorsal thalami and periaqueductal grey matter.

MRI

In Wernicke-Korsakoff Syndrome patients, MRI may show the following changes [1]:

  • Atrophy of mamillary bodies.
  • Hyperintense signals in the mesial dorsal thalami
  • Hyperintense signals in the periaqueductal grey matter
  • On T1 C+ MRI, contrast enhancement in the aforementioned regions.
  • DWI/ADC: Restricted diffusion in the same regions.
  • MR spectroscopy: Reduced N-acetylaspartic acid and increased lactate concentrations.
Selected FLAIR MRI images of the brain demonstrates hyperintensities in the periaqueductal region and the medial thalami. Case courtesy of A.Prof Frank Gaillard. [2]


References

  1. Jan K (2018). "Wernicke encephalopathy: (MRI) picture worth a thousand words". Oxf Med Case Reports. 2018 (5): omy013. doi:10.1093/omcr/omy013. PMC 5965079. PMID 29868178.
  2. https://radiopaedia.org/cases/12149">rID: 12149


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